{"id":2378,"date":"2026-09-27T11:38:51","date_gmt":"2026-09-27T04:38:51","guid":{"rendered":"https:\/\/cpc1.vn\/tinh-bot-hydroxypropyl\/"},"modified":"2026-09-27T11:38:51","modified_gmt":"2026-09-27T04:38:51","slug":"tinh-bot-hydroxypropyl","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/tinh-bot-hydroxypropyl\/","title":{"rendered":"Tinh b\u1ed9t hydroxypropyl (E1440) \u2013 t\u00e1 d\u01b0\u1ee3c d\u00ednh, r\u00e3, l\u00e0m \u0111\u1eb7c"},"content":{"rendered":"

Tinh b\u1ed9t hydroxypropyl (E1440) \u2013 t\u00e1 d\u01b0\u1ee3c d\u00ednh, r\u00e3, l\u00e0m \u0111\u1eb7c<\/h1>\n

Tinh b\u1ed9t hydroxypropyl<\/strong> (hydroxypropyl starch, E1440) l\u00e0 tinh b\u1ed9t bi\u1ebfn t\u00ednh \u2013 ether hydroxypropyl c\u1ee7a tinh b\u1ed9t (JPE m\u00f4 t\u1ea3 t\u1eeb tinh b\u1ed9t ng\u00f4). Ch\u1ea5t n\u00e0y \u0111\u01b0\u1ee3c d\u00f9ng l\u00e0m t\u00e1 d\u01b0\u1ee3c d\u00ednh, t\u00e1 d\u01b0\u1ee3c r\u00e3, ch\u1ea5t nh\u0169 h\u00f3a v\u00e0 ch\u1ea5t l\u00e0m \u0111\u1eb7c; \u0111\u00e1ng ch\u00fa \u00fd l\u00e0 \u1ee9ng d\u1ee5ng trong v\u1ecf nang m\u1ec1m kh\u00f4ng d\u00f9ng gelatin<\/strong>.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\nHydroxylpropyl starch, E1440<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n113894-92-1<\/td>\n<\/tr>\n
Th\u00e0nh ph\u1ea7n<\/td>\nNh\u00f3m hydroxypropyl 2,0\u20137,0% (JPE, sau khi s\u1ea5y)<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nT\u00e1 d\u01b0\u1ee3c d\u00ednh, t\u00e1 d\u01b0\u1ee3c r\u00e3, ch\u1ea5t nh\u0169 h\u00f3a, ch\u1ea5t l\u00e0m \u0111\u1eb7c, t\u0103ng \u0111\u1ed9 nh\u1edbt<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Applications<\/h2>\n
    \n
  • Ph\u1ed1i h\u1ee3p carrageenan \u0111\u1ec3 s\u1ea3n xu\u1ea5t v\u1ecf nang m\u1ec1m<\/strong> (thay gelatin \u2013 ph\u00f9 h\u1ee3p s\u1ea3n ph\u1ea9m chay, halal).<\/li>\n
  • Th\u1ef1c nghi\u1ec7m: c\u1ed1t th\u00e2n n\u01b0\u1edbc cho vi\u00ean gi\u1ea3i ph\u00f3ng c\u00f3 ki\u1ec3m so\u00e1t, k\u1ec3 c\u1ea3 b\u1eb1ng d\u1eadp th\u1eb3ng; d\u1eabn ch\u1ea5t tinh b\u1ed9t hydroxypropyl\u2013methyl methacrylat (HS-MMA) cho c\u1ed1t d\u1eadp th\u1eb3ng.<\/li>\n
  • Tinh b\u1ed9t hydroxypropyl ti\u1ec1n gelatin h\u00f3a r\u00e3 t\u1ed1t v\u00e0 d\u00f9ng l\u00e0m t\u00e1 d\u01b0\u1ee3c d\u00ednh khi x\u00e1t h\u1ea1t \u01b0\u1edbt.<\/li>\n
  • C\u00f3 trong ch\u1ebf ph\u1ea9m s\u00e1t khu\u1ea9n; d\u00f9ng r\u1ed9ng r\u00e3i trong m\u1ef9 ph\u1ea9m; polyme t\u1ea1o pha n\u01b0\u1edbc trong ph\u00e2n t\u00e1ch sinh h\u1ecdc.<\/li>\n<\/ul>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • B\u1ed9t th\u00f4 tr\u01a1n ch\u1ea3y, tr\u1eafng \u0111\u1ebfn tr\u1eafng ng\u00e0.<\/li>\n
    • pH h\u1ec7 ph\u00e2n t\u00e1n 10%: 4,5\u20137,0.<\/li>\n
    • H\u1ea7u nh\u01b0 kh\u00f4ng tan trong n\u01b0\u1edbc (l\u1ea1nh), ethanol 95%, ether.<\/li>\n<\/ul>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n

      B\u1ec1n \u1edf \u0111\u1ed9 \u1ea9m cao v\u00e0 \u0111\u01b0\u1ee3c xem l\u00e0 tr\u01a1 trong \u0111i\u1ec1u ki\u1ec7n th\u01b0\u1eddng; b\u1ec1n trong h\u1ec7 nh\u0169 t\u01b0\u01a1ng \u1edf pH 3\u20139.<\/p>\n

      S\u1ea3n xu\u1ea5t<\/h2>\n

      T\u1eeb tinh b\u1ed9t t\u1ef1 nhi\u00ean, d\u00f9ng propylen oxyd l\u00e0m t\u00e1c nh\u00e2n bi\u1ebfn t\u00ednh trong m\u00f4i tr\u01b0\u1eddng ki\u1ec1m \u2013 g\u1eafn nh\u00f3m hydroxypropyl v\u00e0o v\u1ecb tr\u00ed OH b\u1eb1ng li\u00ean k\u1ebft ether.<\/p>\n

      An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n

      D\u00f9ng r\u1ed9ng r\u00e3i trong m\u1ef9 ph\u1ea9m, th\u1ef1c ph\u1ea9m v\u00e0 thu\u1ed1c u\u1ed1ng. WHO x\u1ebfp ADI “kh\u00f4ng gi\u1edbi h\u1ea1n” do dung n\u1ea1p t\u1ed1t khi u\u1ed1ng. Thao t\u00e1c theo bi\u1ec7n ph\u00e1p th\u00f4ng th\u01b0\u1eddng.<\/p>\n

      T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
        \n
      • FDA x\u1ebfp nh\u00f3m GRAS; \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn l\u00e0 ph\u1ee5 gia th\u1ef1c ph\u1ea9m t\u1ea1i ch\u00e2u \u00c2u (E1440).<\/li>\n
      • C\u00f3 ti\u00eau chu\u1ea9n trong Japanese Pharmaceutical Excipients.<\/li>\n<\/ul>\n

        Ch\u1ea5t li\u00ean quan:<\/strong> tinh b\u1ed9t, tinh b\u1ed9t ti\u1ec1n gelatin h\u00f3a, natri starch glycolat, carrageenan.<\/p>\n

        Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

        N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Hydroxypropyl Starch<\/em> trong:
        \nRowe R.C., Sheskey P.J., Owen S.C. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 5.
        \nPharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2006.
        \nB\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

        \u1ea2nh minh h\u1ecda: thi\u1ebft k\u1ebf c\u1ee7a CPC1.<\/em><\/p>\n

        L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2006.
        \nTi\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh
        \nhi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

        Tinh b\u1ed9t hydroxypropyl (E1440) \u2013 t\u00e1 d\u01b0\u1ee3c d\u00ednh, r\u00e3, l\u00e0m \u0111\u1eb7c Tinh b\u1ed9t hydroxypropyl (hydroxypropyl starch, E1440) l\u00e0 tinh b\u1ed9t bi\u1ebfn t\u00ednh \u2013 ether hydroxypropyl c\u1ee7a tinh b\u1ed9t (JPE m\u00f4 t\u1ea3 t\u1eeb tinh b\u1ed9t ng\u00f4). Ch\u1ea5t n\u00e0y \u0111\u01b0\u1ee3c d\u00f9ng l\u00e0m t\u00e1 d\u01b0\u1ee3c d\u00ednh, t\u00e1 d\u01b0\u1ee3c r\u00e3, ch\u1ea5t nh\u0169 h\u00f3a v\u00e0 ch\u1ea5t l\u00e0m \u0111\u1eb7c; \u0111\u00e1ng ch\u00fa […]<\/p>","protected":false},"author":1,"featured_media":2377,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-2378","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":[],"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/tinh-bot-hydroxypropyl.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/tinh-bot-hydroxypropyl-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/tinh-bot-hydroxypropyl-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/tinh-bot-hydroxypropyl-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/tinh-bot-hydroxypropyl-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/tinh-bot-hydroxypropyl.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/tinh-bot-hydroxypropyl.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/tinh-bot-hydroxypropyl-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Tinh b\u1ed9t hydroxypropyl (E1440) \u2013 t\u00e1 d\u01b0\u1ee3c d\u00ednh, r\u00e3, l\u00e0m \u0111\u1eb7c Tinh b\u1ed9t hydroxypropyl (hydroxypropyl starch, E1440) l\u00e0 tinh b\u1ed9t bi\u1ebfn t\u00ednh \u2013 ether hydroxypropyl c\u1ee7a tinh b\u1ed9t (JPE m\u00f4 t\u1ea3 t\u1eeb tinh b\u1ed9t ng\u00f4). Ch\u1ea5t n\u00e0y \u0111\u01b0\u1ee3c d\u00f9ng l\u00e0m t\u00e1 d\u01b0\u1ee3c d\u00ednh, t\u00e1 d\u01b0\u1ee3c r\u00e3, ch\u1ea5t nh\u0169 h\u00f3a v\u00e0 ch\u1ea5t l\u00e0m \u0111\u1eb7c; \u0111\u00e1ng ch\u00fa…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2378","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=2378"}],"version-history":[{"count":0,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2378\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2377"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=2378"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=2378"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=2378"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}