{"id":2372,"date":"2026-09-27T11:37:48","date_gmt":"2026-09-27T04:37:48","guid":{"rendered":"https:\/\/cpc1.vn\/hydroxyethylmethyl-cellulose\/"},"modified":"2026-09-28T21:14:28","modified_gmt":"2026-09-28T14:14:28","slug":"hydroxyethylmethyl-cellulose","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/hydroxyethylmethyl-cellulose\/","title":{"rendered":"Hydroxyethylmethyl cellulose (HEMC) \u2013 t\u00e1 d\u01b0\u1ee3c l\u00e0m \u0111\u1eb7c, d\u00ednh, t\u1ea1o h\u1ed7n d\u1ecbch"},"content":{"rendered":"

Hydroxyethylmethyl cellulose (HEMC) \u2013 t\u00e1 d\u01b0\u1ee3c l\u00e0m \u0111\u1eb7c, d\u00ednh, t\u1ea1o h\u1ed7n d\u1ecbch<\/h1>\n

Hydroxyethylmethyl cellulose<\/strong> (HEMC, MHEC, hymetellose) l\u00e0 cellulose \u0111\u01b0\u1ee3c O-methyl h\u00f3a v\u00e0 O-(2-hydroxyethyl) h\u00f3a m\u1ed9t ph\u1ea7n. T\u00ednh ch\u1ea5t g\u1ea7n gi\u1ed1ng methylcellulose, nh\u01b0ng nh\u00f3m hydroxyethyl gi\u00fap tan trong n\u01b0\u1edbc d\u1ec5 h\u01a1n, ch\u1ecbu mu\u1ed1i t\u1ed1t h\u01a1n v\u00e0 c\u00f3 nhi\u1ec7t \u0111\u1ed9 keo t\u1ee5 cao h\u01a1n<\/strong>.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\nHEMC, MHEC, hymetellose, hydroxyethyl methylcellulose, methylhydroxyethylcellulose; Culminal MHEC, Tylopur MH\/MHB, Tylose MB\/MH\/MHB<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n9032-42-2<\/td>\n<\/tr>\n
C\u1ea5u t\u1ea1o<\/td>\nCellulose O-methyl h\u00f3a v\u00e0 O-(2-hydroxyethyl) h\u00f3a m\u1ed9t ph\u1ea7n; c\u00e1c c\u1ea5p mang s\u1ed1 ch\u1ec9 \u0111\u1ed9 nh\u1edbt bi\u1ec3u ki\u1ebfn (mPa\u00b7s) c\u1ee7a dung d\u1ecbch 2% \u1edf 20 \u00b0C<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nT\u00e1 d\u01b0\u1ee3c bao, t\u1ea1o h\u1ed7n d\u1ecbch, t\u00e1 d\u01b0\u1ee3c d\u00ednh vi\u00ean n\u00e9n, ch\u1ea5t l\u00e0m \u0111\u1eb7c, t\u0103ng \u0111\u1ed9 nh\u1edbt<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Applications<\/h2>\n
    \n
  • T\u00e1 d\u01b0\u1ee3c trong vi\u00ean n\u00e9n u\u1ed1ng, h\u1ed7n d\u1ecbch u\u1ed1ng v\u00e0 gel d\u00f9ng ngo\u00e0i.<\/li>\n
  • Vai tr\u00f2 t\u01b0\u01a1ng t\u1ef1 methylcellulose v\u00e0 hypromellose: l\u00e0m \u0111\u1eb7c, t\u1ea1o h\u1ed7n d\u1ecbch, t\u00e1 d\u01b0\u1ee3c d\u00ednh, t\u1ea1o m\u00e0ng bao.<\/li>\n
  • L\u1ee3i th\u1ebf so v\u1edbi methylcellulose: tan n\u01b0\u1edbc d\u1ec5 h\u01a1n, dung d\u1ecbch ch\u1ecbu mu\u1ed1i t\u1ed1t h\u01a1n, nhi\u1ec7t \u0111\u1ed9 keo t\u1ee5 khi \u0111un cao h\u01a1n.<\/li>\n<\/ul>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • B\u1ed9t ho\u1eb7c h\u1ea1t tr\u1eafng, tr\u1eafng ng\u00e0 ho\u1eb7c tr\u1eafng x\u00e1m; h\u00fat \u1ea9m sau khi s\u1ea5y.<\/li>\n
    • pH dung d\u1ecbch 2%: 5,5\u20138,0; \u0111\u1ed9 \u1ea9m \u2264 10%.<\/li>\n
    • \u0110\u1ed9 nh\u1edbt kho\u1ea3ng 22\u201330 mPa\u00b7s cho dung d\u1ecbch 2% \u1edf 20 \u00b0C (t\u00f9y c\u1ea5p).<\/li>\n
    • Tan trong n\u01b0\u1edbc l\u1ea1nh t\u1ea1o dung d\u1ecbch keo; h\u1ea7u nh\u01b0 kh\u00f4ng tan trong n\u01b0\u1edbc n\u00f3ng (tr\u00ean 60 \u00b0C), aceton, ethanol 95%, ether, toluen.<\/li>\n<\/ul>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n

      H\u00fat \u1ea9m \u2013 b\u1ea3o qu\u1ea3n n\u01a1i kh\u00f4, tr\u00e1nh nhi\u1ec7t.<\/p>\n

      An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n

      D\u00f9ng trong nhi\u1ec1u ch\u1ebf ph\u1ea9m u\u1ed1ng v\u00e0 d\u00f9ng ngo\u00e0i, \u0111\u01b0\u1ee3c xem l\u00e0 g\u1ea7n nh\u01b0 kh\u00f4ng \u0111\u1ed9c, kh\u00f4ng k\u00edch \u1ee9ng. D\u00f9ng k\u00ednh v\u00e0 g\u0103ng tay khi thao t\u00e1c.<\/p>\n

      T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
        \n
      • \u0110\u01b0\u1ee3c li\u1ec7t k\u00ea GRAS; c\u00f3 trong thu\u1ed1c kh\u00f4ng ti\u00eam \u0111\u01b0\u1ee3c c\u1ea5p ph\u00e9p t\u1ea1i ch\u00e2u \u00c2u (h\u1ed7n d\u1ecbch u\u1ed1ng, vi\u00ean n\u00e9n, ch\u1ebf ph\u1ea9m d\u00f9ng ngo\u00e0i).<\/li>\n
      • C\u00f3 chuy\u00ean lu\u1eadn trong Ph.Eur.<\/li>\n<\/ul>\n

        Ch\u1ea5t li\u00ean quan:<\/strong> ethylcellulose, hydroxyethyl cellulose, hypromellose, methylcellulose.<\/p>\n

        Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

        N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Hydroxyethylmethyl Cellulose<\/em> trong: Rowe R.C., Sheskey P.J., Owen S.C. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 5. Pharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2006. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

        \u1ea2nh minh h\u1ecda: thi\u1ebft k\u1ebf c\u1ee7a CPC1.<\/em><\/p>\n

        L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2006. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

        Hydroxyethylmethyl cellulose (HEMC) \u2013 t\u00e1 d\u01b0\u1ee3c l\u00e0m \u0111\u1eb7c, d\u00ednh, t\u1ea1o h\u1ed7n d\u1ecbch Hydroxyethylmethyl cellulose (HEMC, MHEC, hymetellose) l\u00e0 cellulose \u0111\u01b0\u1ee3c O-methyl h\u00f3a v\u00e0 O-(2-hydroxyethyl) h\u00f3a m\u1ed9t ph\u1ea7n. T\u00ednh ch\u1ea5t g\u1ea7n gi\u1ed1ng methylcellulose, nh\u01b0ng nh\u00f3m hydroxyethyl gi\u00fap tan trong n\u01b0\u1edbc d\u1ec5 h\u01a1n, ch\u1ecbu mu\u1ed1i t\u1ed1t h\u01a1n v\u00e0 c\u00f3 nhi\u1ec7t \u0111\u1ed9 keo t\u1ee5 cao h\u01a1n. Th\u00f4ng tin […]<\/p>","protected":false},"author":1,"featured_media":2371,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-2372","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":[],"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/hydroxyethylmethyl-cellulose.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/hydroxyethylmethyl-cellulose-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/hydroxyethylmethyl-cellulose-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/hydroxyethylmethyl-cellulose-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/hydroxyethylmethyl-cellulose-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/hydroxyethylmethyl-cellulose.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/hydroxyethylmethyl-cellulose.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/hydroxyethylmethyl-cellulose-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Hydroxyethylmethyl cellulose (HEMC) \u2013 t\u00e1 d\u01b0\u1ee3c l\u00e0m \u0111\u1eb7c, d\u00ednh, t\u1ea1o h\u1ed7n d\u1ecbch Hydroxyethylmethyl cellulose (HEMC, MHEC, hymetellose) l\u00e0 cellulose \u0111\u01b0\u1ee3c O-methyl h\u00f3a v\u00e0 O-(2-hydroxyethyl) h\u00f3a m\u1ed9t ph\u1ea7n. T\u00ednh ch\u1ea5t g\u1ea7n gi\u1ed1ng methylcellulose, nh\u01b0ng nh\u00f3m hydroxyethyl gi\u00fap tan trong n\u01b0\u1edbc d\u1ec5 h\u01a1n, ch\u1ecbu mu\u1ed1i t\u1ed1t h\u01a1n v\u00e0 c\u00f3 nhi\u1ec7t \u0111\u1ed9 keo t\u1ee5 cao h\u01a1n. Th\u00f4ng tin…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2372","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=2372"}],"version-history":[{"count":1,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2372\/revisions"}],"predecessor-version":[{"id":3255,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2372\/revisions\/3255"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2371"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=2372"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=2372"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=2372"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}