{"id":2354,"date":"2026-09-27T11:32:10","date_gmt":"2026-09-27T04:32:10","guid":{"rendered":"https:\/\/cpc1.vn\/glyceryl-palmitostearat\/"},"modified":"2026-09-29T12:02:25","modified_gmt":"2026-09-29T05:02:25","slug":"glyceryl-palmitostearat","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/glyceryl-palmitostearat\/","title":{"rendered":"Glyceryl palmitostearat (Precirol ATO 5) \u2013 c\u1ed1t lipid, che v\u1ecb, t\u00e1 d\u01b0\u1ee3c tr\u01a1n"},"content":{"rendered":"

Glyceryl palmitostearat (Precirol ATO 5) \u2013 c\u1ed1t lipid, che v\u1ecb, t\u00e1 d\u01b0\u1ee3c tr\u01a1n<\/h1>\n

Glyceryl palmitostearat<\/strong> (Precirol ATO 5) l\u00e0 h\u1ed7n h\u1ee3p mono-, di- v\u00e0 triglycerid c\u1ee7a acid b\u00e9o C16 v\u00e0 C18. Trong d\u1ea1ng b\u00e0o ch\u1ebf r\u1eafn \u0111\u01b0\u1eddng u\u1ed1ng, ch\u1ea5t n\u00e0y \u0111\u01b0\u1ee3c d\u00f9ng l\u00e0m c\u1ed1t lipid gi\u1ea3i ph\u00f3ng k\u00e9o d\u00e0i<\/strong>, ch\u1ea5t che v\u1ecb<\/strong> v\u00e0 t\u00e1 d\u01b0\u1ee3c tr\u01a1n.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\nGlycerol palmitostearate, glycerin palmitostearate; Precirol ATO 5<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n8067-32-1<\/td>\n<\/tr>\n
Th\u00e0nh ph\u1ea7n<\/td>\nH\u1ed7n h\u1ee3p mono-, di-, triglycerid c\u1ee7a acid palmitic (C16) v\u00e0 stearic (C18); 1-monoglycerid 8,0\u201317,0%<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nV\u1eadt li\u1ec7u ph\u00e2n h\u1ee7y sinh h\u1ecdc, t\u00e1 d\u01b0\u1ee3c bao, t\u1ea1o gel, \u0111i\u1ec1u ch\u1ec9nh gi\u1ea3i ph\u00f3ng, t\u00e1 d\u01b0\u1ee3c \u0111\u1ed9n, t\u00e1 d\u01b0\u1ee3c tr\u01a1n, che v\u1ecb<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u1ee8ng d\u1ee5ng v\u00e0 n\u1ed3ng \u0111\u1ed9<\/h2>\n\n\n\n\n\n\n\n
Vai tr\u00f2<\/th>\nN\u1ed3ng \u0111\u1ed9 (%)<\/th>\n<\/tr>\n<\/thead>\n
C\u1ed1t gi\u1ea3i ph\u00f3ng k\u00e9o d\u00e0i<\/td>\n10,0\u201325,0<\/td>\n<\/tr>\n
Che v\u1ecb<\/td>\n2,0\u20136,0<\/td>\n<\/tr>\n
T\u00e1 d\u01b0\u1ee3c tr\u01a1n vi\u00ean n\u00e9n<\/td>\n1,0\u20133,0<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
    \n
  • T\u00e1 d\u01b0\u1ee3c tr\u01a1n<\/strong>: th\u1eddi gian tr\u1ed9n c\u00e0ng d\u00e0i, th\u1eddi gian r\u00e3 c\u00e0ng t\u0103ng v\u00e0 \u0111\u1ed9 c\u1ee9ng vi\u00ean c\u00e0ng gi\u1ea3m \u2013 c\u1ea7n ki\u1ec3m so\u00e1t th\u1eddi gian tr\u1ed9n.<\/li>\n
  • C\u1ed1t th\u00e2n d\u1ea7u<\/strong> cho vi\u00ean v\u00e0 nang gi\u1ea3i ph\u00f3ng k\u00e9o d\u00e0i, b\u00e0o ch\u1ebf b\u1eb1ng x\u00e1t h\u1ea1t ho\u1eb7c k\u1ef9 thu\u1eadt n\u00f3ng ch\u1ea3y (x\u00e1t h\u1ea1t cho gi\u1ea3i ph\u00f3ng nhanh h\u01a1n); h\u00e0m l\u01b0\u1ee3ng c\u00e0ng cao gi\u1ea3i ph\u00f3ng c\u00e0ng ch\u1eadm.<\/li>\n
  • Vi c\u1ea7u (\u0111\u00f3ng nang ho\u1eb7c d\u1eadp vi\u00ean), pellet, h\u1ea1t bao, gel ph\u00e2n h\u1ee7y sinh h\u1ecdc.<\/li>\n<\/ul>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • N\u00f3ng ch\u1ea3y 52\u201355 \u00b0C; s\u00f4i kho\u1ea3ng 200 \u00b0C.<\/li>\n
    • Ch\u1ec9 s\u1ed1 acid < 6,0; ch\u1ec9 s\u1ed1 hydroxyl 60\u2013115; ch\u1ec9 s\u1ed1 iod < 3; ch\u1ec9 s\u1ed1 x\u00e0 ph\u00f2ng h\u00f3a 175\u2013195; glycerin t\u1ef1 do < 1,0%.<\/li>\n
    • D\u1ec5 tan trong cloroform, diclomethan; h\u1ea7u nh\u01b0 kh\u00f4ng tan trong ethanol 95%, d\u1ea7u kho\u00e1ng, n\u01b0\u1edbc.<\/li>\n<\/ul>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n

      Kh\u00f4ng b\u1ea3o qu\u1ea3n tr\u00ean 35 \u00b0C. B\u1ea3o qu\u1ea3n l\u00e2u h\u01a1n 1 th\u00e1ng n\u00ean \u0111\u1ec3 \u1edf 5\u201315 \u00b0C trong bao b\u00ec k\u00edn kh\u00ed, tr\u00e1nh \u00e1nh s\u00e1ng v\u00e0 \u1ea9m.<\/p>\n

      T\u01b0\u01a1ng k\u1ef5<\/h2>\n

      \u0110\u00e3 ghi nh\u1eadn t\u01b0\u01a1ng k\u1ef5 v\u1edbi ketoprofen v\u00e0 naproxen.<\/p>\n

      S\u1ea3n xu\u1ea5t<\/h2>\n

      Ester h\u00f3a tr\u1ef1c ti\u1ebfp acid palmitic v\u00e0 stearic v\u1edbi glycerol, kh\u00f4ng d\u00f9ng x\u00fac t\u00e1c.<\/p>\n

      An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n

      D\u00f9ng trong thu\u1ed1c u\u1ed1ng, \u0111\u01b0\u1ee3c xem l\u00e0 g\u1ea7n nh\u01b0 kh\u00f4ng \u0111\u1ed9c, kh\u00f4ng k\u00edch \u1ee9ng. Thao t\u00e1c theo bi\u1ec7n ph\u00e1p th\u00f4ng th\u01b0\u1eddng.<\/p>\n

      T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
        \n
      • FDA x\u1ebfp nh\u00f3m GRAS; c\u00f3 trong FDA Inactive Ingredients Guide (h\u1ed7n d\u1ecbch, vi\u00ean n\u00e9n u\u1ed1ng).<\/li>\n
      • C\u00f3 trong thu\u1ed1c kh\u00f4ng d\u00f9ng \u0111\u01b0\u1eddng ti\u00eam \u0111\u01b0\u1ee3c c\u1ea5p ph\u00e9p t\u1ea1i ch\u00e2u \u00c2u; c\u00f3 trong danh m\u1ee5c t\u00e1 d\u01b0\u1ee3c \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn c\u1ee7a Canada.<\/li>\n<\/ul>\n

        Ch\u1ea5t li\u00ean quan:<\/strong> glyceryl behenat, glyceryl monostearat.<\/p>\n

        Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

        N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Glyceryl Palmitostearate<\/em> trong: Rowe R.C., Sheskey P.J., Owen S.C. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 5. Pharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2006. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

        \u1ea2nh minh h\u1ecda: thi\u1ebft k\u1ebf c\u1ee7a CPC1.<\/em><\/p>\n

        L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2006. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

        Glyceryl palmitostearat (Precirol ATO 5) \u2013 c\u1ed1t lipid, che v\u1ecb, t\u00e1 d\u01b0\u1ee3c tr\u01a1n Glyceryl palmitostearat (Precirol ATO 5) l\u00e0 h\u1ed7n h\u1ee3p mono-, di- v\u00e0 triglycerid c\u1ee7a acid b\u00e9o C16 v\u00e0 C18. Trong d\u1ea1ng b\u00e0o ch\u1ebf r\u1eafn \u0111\u01b0\u1eddng u\u1ed1ng, ch\u1ea5t n\u00e0y \u0111\u01b0\u1ee3c d\u00f9ng l\u00e0m c\u1ed1t lipid gi\u1ea3i ph\u00f3ng k\u00e9o d\u00e0i, ch\u1ea5t che v\u1ecb v\u00e0 t\u00e1 d\u01b0\u1ee3c […]<\/p>\n","protected":false},"author":1,"featured_media":2353,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-2354","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glyceryl-palmitostearat.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glyceryl-palmitostearat-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glyceryl-palmitostearat-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glyceryl-palmitostearat-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glyceryl-palmitostearat-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glyceryl-palmitostearat.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glyceryl-palmitostearat.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glyceryl-palmitostearat-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Glyceryl palmitostearat (Precirol ATO 5) \u2013 c\u1ed1t lipid, che v\u1ecb, t\u00e1 d\u01b0\u1ee3c tr\u01a1n Glyceryl palmitostearat (Precirol ATO 5) l\u00e0 h\u1ed7n h\u1ee3p mono-, di- v\u00e0 triglycerid c\u1ee7a acid b\u00e9o C16 v\u00e0 C18. Trong d\u1ea1ng b\u00e0o ch\u1ebf r\u1eafn \u0111\u01b0\u1eddng u\u1ed1ng, ch\u1ea5t n\u00e0y \u0111\u01b0\u1ee3c d\u00f9ng l\u00e0m c\u1ed1t lipid gi\u1ea3i ph\u00f3ng k\u00e9o d\u00e0i, ch\u1ea5t che v\u1ecb v\u00e0 t\u00e1 d\u01b0\u1ee3c…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2354","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=2354"}],"version-history":[{"count":2,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2354\/revisions"}],"predecessor-version":[{"id":3830,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2354\/revisions\/3830"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2353"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=2354"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=2354"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=2354"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}