{"id":2304,"date":"2026-09-27T11:18:35","date_gmt":"2026-09-27T04:18:35","guid":{"rendered":"https:\/\/cpc1.vn\/dimethyl-phthalat\/"},"modified":"2026-09-27T11:18:35","modified_gmt":"2026-09-27T04:18:35","slug":"dimethyl-phthalat","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/dimethyl-phthalat\/","title":{"rendered":"Dimethyl phthalat (DMP) \u2013 ch\u1ea5t h\u00f3a d\u1ebbo v\u00e0 dung m\u00f4i cho m\u00e0ng bao"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Dimethyl phthalat (DMP) \u2013 ch\u1ea5t h\u00f3a d\u1ebbo v\u00e0 dung m\u00f4i cho m\u00e0ng bao<\/h1>\n<p><strong>Dimethyl phthalat<\/strong> (DMP) l\u00e0 ester methyl c\u1ee7a acid phthalic \u2013 phthalat nh\u1ecf nh\u1ea5t v\u00e0 ph\u00e2n c\u1ef1c nh\u1ea5t trong nh\u00f3m. Trong d\u01b0\u1ee3c ph\u1ea9m, DMP \u0111\u01b0\u1ee3c d\u00f9ng l\u00e0m <strong>dung m\u00f4i v\u00e0 ch\u1ea5t h\u00f3a d\u1ebbo<\/strong> cho m\u00e0ng bao (HPMC, cellulose acetat, h\u1ed7n h\u1ee3p cellulose acetat\u2013butyrat); ngo\u00e0i ra l\u00e0 ho\u1ea1t ch\u1ea5t xua c\u00f4n tr\u00f9ng d\u00f9ng ngo\u00e0i ph\u1ed5 bi\u1ebfn.<\/p>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean kh\u00e1c<\/td>\n<td>DMP, dimethyl o-phthalate, dimethyl 1,2-benzenedicarboxylate, phthalic acid dimethyl ester; Palatinol M, Kodaflex DMP, Unimoll DM, Solvanom\u2026<\/td>\n<\/tr>\n<tr>\n<td>S\u1ed1 CAS<\/td>\n<td>131-11-3<\/td>\n<\/tr>\n<tr>\n<td>C\u00f4ng th\u1ee9c \u2013 KLPT<\/td>\n<td>C<sub>10<\/sub>H<sub>10<\/sub>O<sub>4<\/sub> \u2013 194,19<\/td>\n<\/tr>\n<tr>\n<td>Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\n<td>Ch\u1ea5t t\u1ea1o m\u00e0ng, ch\u1ea5t h\u00f3a d\u1ebbo, dung m\u00f4i<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>Applications<\/h2>\n<ul>\n<li>Dung m\u00f4i v\u00e0 ch\u1ea5t h\u00f3a d\u1ebbo cho m\u00e0ng bao hydroxypropyl methylcellulose, cellulose acetat, cellulose acetat\u2013butyrat.<\/li>\n<li>Ch\u1ea5t xua c\u00f4n tr\u00f9ng d\u00f9ng ngo\u00e0i, th\u01b0\u1eddng \u1edf d\u1ea1ng kem ho\u1eb7c lotion 40%; t\u1eebng d\u00f9ng x\u1eed l\u00fd v\u1ea3i l\u1ec1u tr\u1ea1i.<\/li>\n<li>Nhi\u1ec1u \u1ee9ng d\u1ee5ng c\u00f4ng nghi\u1ec7p.<\/li>\n<\/ul>\n<h2>M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n<ul>\n<li>Ch\u1ea5t l\u1ecfng d\u1ea1ng d\u1ea7u s\u00e1nh, kh\u00f4ng m\u00e0u ho\u1eb7c h\u01a1i c\u00f3 m\u00e0u, kh\u00f4ng m\u00f9i.<\/li>\n<li>Nhi\u1ec7t \u0111\u1ed9 s\u00f4i 280 \u00b0C (ph\u00e2n h\u1ee7y); n\u00f3ng ch\u1ea3y 2,0\u20135,5 \u00b0C (s\u1ea3n ph\u1ea9m th\u01b0\u01a1ng m\u1ea1i \u0111\u00f4ng \u0111\u1eb7c \u1edf kho\u1ea3ng 0 \u00b0C); \u0111i\u1ec3m ch\u1edbp ch\u00e1y 146 \u00b0C (c\u1ed1c k\u00edn).<\/li>\n<li>T\u1ef7 tr\u1ecdng 1,186\u20131,192 g\/cm\u00b3; chi\u1ebft su\u1ea5t 1,515\u20131,517; \u0111\u1ed9 nh\u1edbt 17,2 mPa\u00b7s (25 \u00b0C).<\/li>\n<li>H\u1ec7 s\u1ed1 ph\u00e2n b\u1ed1 octanol:n\u01b0\u1edbc 1,56 (\u00edt th\u00e2n d\u1ea7u h\u01a1n DEP, DBP).<\/li>\n<li>Tan 1\/250 trong n\u01b0\u1edbc, 1\/294 trong d\u1ea7u kho\u00e1ng; tr\u1ed9n l\u1eabn v\u1edbi ethanol 95%, ether, cloroform, benzen.<\/li>\n<\/ul>\n<h2>\u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n<p>Nh\u1ea1y v\u1edbi \u00e1nh s\u00e1ng k\u00e9o d\u00e0i \u2013 b\u1ea3o qu\u1ea3n n\u01a1i m\u00e1t, t\u1ed1i, kh\u00f4, th\u00f4ng tho\u00e1ng, tr\u00e1nh va \u0111\u1eadp, c\u00e1ch ly ch\u1ea5t t\u01b0\u01a1ng k\u1ef5. Bao b\u00ec r\u1ed7ng v\u1eabn nguy hi\u1ec3m do c\u00f2n h\u01a1i v\u00e0 c\u1eb7n. Nguy c\u01a1 ch\u00e1y nh\u1eb9 khi g\u1eb7p nhi\u1ec7t; tr\u00ean \u0111i\u1ec3m ch\u1edbp ch\u00e1y c\u00f3 th\u1ec3 t\u1ea1o h\u1ed7n h\u1ee3p h\u01a1i\u2013kh\u00f4ng kh\u00ed d\u1ec5 n\u1ed5. Dung d\u1ecbch trong aceton, DMSO, ethanol, n\u01b0\u1edbc b\u1ec1n 24 gi\u1edd \u1edf \u0111i\u1ec1u ki\u1ec7n ph\u00f2ng th\u00ed nghi\u1ec7m.<\/p>\n<h2>T\u01b0\u01a1ng k\u1ef5<\/h2>\n<p>T\u01b0\u01a1ng k\u1ef5 v\u1edbi acid, base m\u1ea1nh, nitrat v\u00e0 ch\u1ea5t oxy h\u00f3a m\u1ea1nh.<\/p>\n<h2>S\u1ea3n xu\u1ea5t<\/h2>\n<p>T\u1eeb anhydrid phthalic v\u00e0 methanol.<\/p>\n<h2>An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n<p>DMP c\u00f3 th\u1ec3 k\u00edch \u1ee9ng m\u1eaft, ni\u00eam m\u1ea1c (\u00edt h\u01a1n DEP) v\u00e0 \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p khi h\u00edt; nu\u1ed1t ph\u1ea3i g\u00e2y n\u00f3ng r\u00e1t mi\u1ec7ng, n\u00f4n, ti\u00eau ch\u1ea3y. Do \u00edt tan trong n\u01b0\u1edbc v\u00e0 kh\u00e1 tan trong lipid, ph\u01a1i nhi\u1ec5m m\u1ea1n c\u00f3 th\u1ec3 t\u00edch l\u0169y trong m\u00f4, g\u00e2y \u1ee9c ch\u1ebf th\u1ea7n kinh trung \u01b0\u01a1ng. K\u1ebft qu\u1ea3 nghi\u00ean c\u1ee9u tr\u00ean \u0111\u1ed9ng v\u1eadt v\u1ec1 qu\u00e1i thai, \u0111\u1ed9t bi\u1ebfn ch\u01b0a th\u1ed1ng nh\u1ea5t; ch\u01b0a c\u00f3 b\u00e1o c\u00e1o x\u00e1c nh\u1eadn t\u00e1c d\u1ee5ng l\u00ean sinh s\u1ea3n \u1edf ng\u01b0\u1eddi v\u00e0 kh\u00f4ng \u0111\u01b0\u1ee3c xem l\u00e0 ch\u1ea5t g\u00e2y ung th\u01b0. Tr\u00e1nh ti\u1ebfp x\u00fac da, m\u1eaft; \u0111eo k\u00ednh k\u00edn ho\u1eb7c t\u1ea5m che m\u1eb7t khi c\u00f3 nguy c\u01a1 b\u1eafn t\u00f3e; d\u00f9ng m\u1eb7t n\u1ea1 khi \u0111un n\u00f3ng \u0111\u1ebfn ph\u00e2n h\u1ee7y. Gi\u1edbi h\u1ea1n ph\u01a1i nhi\u1ec5m t\u1ea1i Anh: 5 mg\/m\u00b3 (8 gi\u1edd), 10 mg\/m\u00b3 (15 ph\u00fat).<\/p>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n<ul>\n<li>C\u00f3 trong m\u1ed9t s\u1ed1 ch\u1ebf ph\u1ea9m d\u00f9ng ngo\u00e0i.<\/li>\n<li>C\u00f3 chuy\u00ean lu\u1eadn trong BP.<\/li>\n<\/ul>\n<p><strong>Ch\u1ea5t li\u00ean quan:<\/strong> dibutyl phthalat, diethyl phthalat.<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<p>N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn <em>Dimethyl Phthalate<\/em> trong:<br \/>\nRowe R.C., Sheskey P.J., Owen S.C. (ch\u1ee7 bi\u00ean). <em>Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 5.<br \/>\nPharmaceutical Press (London) &amp; American Pharmacists Association (Washington DC), 2006.<br \/>\nB\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n<p><em>\u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n<p><em>L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2006.<br \/>\nTi\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh<br \/>\nhi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Dimethyl phthalat (DMP) \u2013 ch\u1ea5t h\u00f3a d\u1ebbo v\u00e0 dung m\u00f4i cho m\u00e0ng bao Dimethyl phthalat (DMP) l\u00e0 ester methyl c\u1ee7a acid phthalic \u2013 phthalat nh\u1ecf nh\u1ea5t v\u00e0 ph\u00e2n c\u1ef1c nh\u1ea5t trong nh\u00f3m. Trong d\u01b0\u1ee3c ph\u1ea9m, DMP \u0111\u01b0\u1ee3c d\u00f9ng l\u00e0m dung m\u00f4i v\u00e0 ch\u1ea5t h\u00f3a d\u1ebbo cho m\u00e0ng bao (HPMC, cellulose acetat, h\u1ed7n h\u1ee3p cellulose acetat\u2013butyrat); [&hellip;]<\/p>","protected":false},"author":1,"featured_media":2303,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-2304","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":[],"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/dimethyl-phthalat.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/dimethyl-phthalat-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/dimethyl-phthalat-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/dimethyl-phthalat-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/dimethyl-phthalat-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/dimethyl-phthalat.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/dimethyl-phthalat.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/dimethyl-phthalat-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Dimethyl phthalat (DMP) \u2013 ch\u1ea5t h\u00f3a d\u1ebbo v\u00e0 dung m\u00f4i cho m\u00e0ng bao Dimethyl phthalat (DMP) l\u00e0 ester methyl c\u1ee7a acid phthalic \u2013 phthalat nh\u1ecf nh\u1ea5t v\u00e0 ph\u00e2n c\u1ef1c nh\u1ea5t trong nh\u00f3m. Trong d\u01b0\u1ee3c ph\u1ea9m, DMP \u0111\u01b0\u1ee3c d\u00f9ng l\u00e0m dung m\u00f4i v\u00e0 ch\u1ea5t h\u00f3a d\u1ebbo cho m\u00e0ng bao (HPMC, cellulose acetat, h\u1ed7n h\u1ee3p cellulose acetat\u2013butyrat);&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2304","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=2304"}],"version-history":[{"count":0,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2304\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2303"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=2304"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=2304"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=2304"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}