{"id":2296,"date":"2026-09-27T11:16:27","date_gmt":"2026-09-27T04:16:27","guid":{"rendered":"https:\/\/cpc1.vn\/diethyl-phthalat\/"},"modified":"2026-09-29T11:59:29","modified_gmt":"2026-09-29T04:59:29","slug":"diethyl-phthalat","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/diethyl-phthalat\/","title":{"rendered":"Diethyl phthalat (DEP) \u2013 ch\u1ea5t h\u00f3a d\u1ebbo m\u00e0ng bao, ch\u1ea5t \u0111\u1ecbnh h\u01b0\u01a1ng"},"content":{"rendered":"

Diethyl phthalat (DEP) \u2013 ch\u1ea5t h\u00f3a d\u1ebbo m\u00e0ng bao, ch\u1ea5t \u0111\u1ecbnh h\u01b0\u01a1ng<\/h1>\n

Diethyl phthalat<\/strong> (DEP) l\u00e0 ester c\u1ee7a acid phthalic v\u1edbi ethanol, d\u00f9ng l\u00e0m ch\u1ea5t h\u00f3a d\u1ebbo<\/strong> cho m\u00e0ng bao vi\u00ean n\u00e9n, h\u1ea1t v\u00e0 c\u1ed1m. DEP c\u00f2n l\u00e0 ch\u1ea5t bi\u1ebfn t\u00ednh c\u1ed3n, dung m\u00f4i cho cellulose acetat v\u00e0 ch\u1ea5t \u0111\u1ecbnh h\u01b0\u01a1ng trong n\u01b0\u1edbc hoa.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\nDEP, ethyl phthalate, ethyl benzene-1,2-dicarboxylate, phthalic acid diethyl ester, Kodaflex DEP<\/td>\n<\/tr>\n
T\u00ean h\u00f3a h\u1ecdc<\/td>\nDiethyl ester c\u1ee7a acid 1,2-benzendicarboxylic<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n84-66-2<\/td>\n<\/tr>\n
C\u00f4ng th\u1ee9c \u2013 KLPT<\/td>\nC12<\/sub>H14<\/sub>O4<\/sub> \u2013 222,24<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nCh\u1ea5t t\u1ea1o m\u00e0ng, ch\u1ea5t h\u00f3a d\u1ebbo, dung m\u00f4i<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Applications<\/h2>\n
    \n
  • Ch\u1ea5t h\u00f3a d\u1ebbo cho m\u00e0ng bao vi\u00ean n\u00e9n, h\u1ea1t, c\u1ed1m \u1edf 10\u201330% so v\u1edbi kh\u1ed1i l\u01b0\u1ee3ng polyme<\/strong>; t\u01b0\u01a1ng h\u1ee3p t\u1ed1t v\u1edbi cellulose acetat, cellulose acetat phthalat.<\/li>\n
  • Ch\u1ea5t bi\u1ebfn t\u00ednh c\u1ed3n; dung m\u00f4i cho cellulose acetat trong s\u1ea3n xu\u1ea5t vecni.<\/li>\n
  • Ch\u1ea5t \u0111\u1ecbnh h\u01b0\u01a1ng trong n\u01b0\u1edbc hoa \u1edf 0,1\u20130,5% kh\u1ed1i l\u01b0\u1ee3ng h\u01b0\u01a1ng.<\/li>\n<\/ul>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • Ch\u1ea5t l\u1ecfng d\u1ea1ng d\u1ea7u trong, kh\u00f4ng m\u00e0u, g\u1ea7n nh\u01b0 kh\u00f4ng m\u00f9i (ho\u1eb7c th\u01a1m r\u1ea5t nh\u1eb9), v\u1ecb \u0111\u1eafng kh\u00f3 ch\u1ecbu.<\/li>\n
    • Nhi\u1ec7t \u0111\u1ed9 s\u00f4i 295 \u00b0C; \u0111i\u1ec3m \u0111\u00f4ng \u0111\u1eb7c kho\u1ea3ng \u221240 \u00b0C; \u0111i\u1ec3m ch\u1edbp ch\u00e1y 160 \u00b0C (c\u1ed1c h\u1edf).<\/li>\n
    • T\u1ef7 tr\u1ecdng 1,120 (25 \u00b0C); chi\u1ebft su\u1ea5t nD<\/sub>25<\/sup> 1,501.<\/li>\n
    • Tr\u1ed9n l\u1eabn v\u1edbi ethanol 95%, ether v\u00e0 nhi\u1ec1u dung m\u00f4i h\u1eefu c\u01a1; h\u1ea7u nh\u01b0 kh\u00f4ng tan trong n\u01b0\u1edbc.<\/li>\n<\/ul>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n

      B\u1ec1n khi \u0111\u1ef1ng trong bao b\u00ec k\u00edn, n\u01a1i kh\u00f4 m\u00e1t.<\/p>\n

      T\u01b0\u01a1ng k\u1ef5<\/h2>\n

      T\u01b0\u01a1ng k\u1ef5 v\u1edbi ch\u1ea5t oxy h\u00f3a m\u1ea1nh.<\/p>\n

      S\u1ea3n xu\u1ea5t<\/h2>\n

      Cho anhydrid phthalic ph\u1ea3n \u1ee9ng v\u1edbi ethanol c\u00f3 acid sulfuric.<\/p>\n

      An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n

      \u1ede m\u1ee9c d\u00f9ng l\u00e0m t\u00e1 d\u01b0\u1ee3c thu\u1ed1c u\u1ed1ng, DEP \u0111\u01b0\u1ee3c xem l\u00e0 kh\u00f4ng \u0111\u1ed9c, kh\u00f4ng k\u00edch \u1ee9ng; u\u1ed1ng l\u01b0\u1ee3ng l\u1edbn c\u00f3 th\u1ec3 g\u00e2y t\u00e1c d\u1ee5ng g\u00e2y m\u00ea v\u00e0 li\u1ec7t th\u1ea7n kinh trung \u01b0\u01a1ng. M\u1ed9t s\u1ed1 nghi\u00ean c\u1ee9u tr\u00ean \u0111\u1ed9ng v\u1eadt g\u1ee3i \u00fd n\u1ed3ng \u0111\u1ed9 cao c\u00f3 th\u1ec3 g\u00e2y qu\u00e1i thai, trong khi nghi\u00ean c\u1ee9u kh\u00e1c kh\u00f4ng th\u1ea5y t\u00e1c d\u1ee5ng b\u1ea5t l\u1ee3i. DEP k\u00edch \u1ee9ng da, m\u1eaft, ni\u00eam m\u1ea1c \u2013 d\u00f9ng qu\u1ea7n \u00e1o b\u1ea3o h\u1ed9, k\u00ednh, g\u0103ng nitril, thao t\u00e1c trong t\u1ee7 h\u1ed1t ho\u1eb7c n\u01a1i th\u00f4ng gi\u00f3, d\u00f9ng m\u1eb7t n\u1ea1. Gi\u1edbi h\u1ea1n ph\u01a1i nhi\u1ec5m t\u1ea1i Anh: 5 mg\/m\u00b3 (8 gi\u1edd), 10 mg\/m\u00b3 (15 ph\u00fat).<\/p>\n

      L\u01b0u \u00fd: sau n\u0103m 2006, vi\u1ec7c d\u00f9ng phthalat l\u00e0m t\u00e1 d\u01b0\u1ee3c \u0111\u01b0\u1ee3c c\u00e1c c\u01a1 quan qu\u1ea3n l\u00fd xem x\u00e9t ch\u1eb7t h\u01a1n; khi ph\u00e1t tri\u1ec3n c\u00f4ng th\u1ee9c m\u1edbi n\u00ean c\u00e2n nh\u1eafc c\u00e1c ch\u1ea5t h\u00f3a d\u1ebbo thay th\u1ebf (triethyl citrat, triacetin, dibutyl sebacat).<\/p>\n

      T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
        \n
      • C\u00f3 trong FDA Inactive Ingredients Guide (vi\u00ean nang, vi\u00ean gi\u1ea3i ph\u00f3ng ch\u1eadm, bao tan trong ru\u1ed9t, gi\u1ea3i ph\u00f3ng k\u00e9o d\u00e0i).<\/li>\n
      • C\u00f3 trong thu\u1ed1c kh\u00f4ng d\u00f9ng \u0111\u01b0\u1eddng ti\u00eam \u0111\u01b0\u1ee3c c\u1ea5p ph\u00e9p t\u1ea1i Anh; c\u00f3 trong danh m\u1ee5c t\u00e1 d\u01b0\u1ee3c \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn c\u1ee7a Canada.<\/li>\n
      • C\u00f3 chuy\u00ean lu\u1eadn trong Ph.Eur. v\u00e0 USP-NF.<\/li>\n<\/ul>\n

        Ch\u1ea5t li\u00ean quan:<\/strong> dibutyl phthalat, dimethyl phthalat.<\/p>\n

        Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

        N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Diethyl Phthalate<\/em> trong: Rowe R.C., Sheskey P.J., Owen S.C. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 5. Pharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2006. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

        \u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n

        L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2006. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

        Diethyl phthalat (DEP) \u2013 ch\u1ea5t h\u00f3a d\u1ebbo m\u00e0ng bao, ch\u1ea5t \u0111\u1ecbnh h\u01b0\u01a1ng Diethyl phthalat (DEP) l\u00e0 ester c\u1ee7a acid phthalic v\u1edbi ethanol, d\u00f9ng l\u00e0m ch\u1ea5t h\u00f3a d\u1ebbo cho m\u00e0ng bao vi\u00ean n\u00e9n, h\u1ea1t v\u00e0 c\u1ed1m. DEP c\u00f2n l\u00e0 ch\u1ea5t bi\u1ebfn t\u00ednh c\u1ed3n, dung m\u00f4i cho cellulose acetat v\u00e0 ch\u1ea5t \u0111\u1ecbnh h\u01b0\u01a1ng trong n\u01b0\u1edbc hoa. Th\u00f4ng […]<\/p>\n","protected":false},"author":1,"featured_media":2295,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-2296","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/diethyl-phthalat.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/diethyl-phthalat-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/diethyl-phthalat-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/diethyl-phthalat-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/diethyl-phthalat-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/diethyl-phthalat.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/diethyl-phthalat.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/diethyl-phthalat-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Diethyl phthalat (DEP) \u2013 ch\u1ea5t h\u00f3a d\u1ebbo m\u00e0ng bao, ch\u1ea5t \u0111\u1ecbnh h\u01b0\u01a1ng Diethyl phthalat (DEP) l\u00e0 ester c\u1ee7a acid phthalic v\u1edbi ethanol, d\u00f9ng l\u00e0m ch\u1ea5t h\u00f3a d\u1ebbo cho m\u00e0ng bao vi\u00ean n\u00e9n, h\u1ea1t v\u00e0 c\u1ed1m. DEP c\u00f2n l\u00e0 ch\u1ea5t bi\u1ebfn t\u00ednh c\u1ed3n, dung m\u00f4i cho cellulose acetat v\u00e0 ch\u1ea5t \u0111\u1ecbnh h\u01b0\u01a1ng trong n\u01b0\u1edbc hoa. Th\u00f4ng…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2296","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=2296"}],"version-history":[{"count":2,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2296\/revisions"}],"predecessor-version":[{"id":3799,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2296\/revisions\/3799"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2295"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=2296"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=2296"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=2296"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}