{"id":2280,"date":"2026-09-27T11:12:24","date_gmt":"2026-09-27T04:12:24","guid":{"rendered":"https:\/\/cpc1.vn\/cyclomethicon\/"},"modified":"2026-09-27T11:12:24","modified_gmt":"2026-09-27T04:12:24","slug":"cyclomethicon","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/cyclomethicon\/","title":{"rendered":"Cyclomethicon \u2013 silicon v\u00f2ng d\u1ec5 bay h\u01a1i cho kem v\u00e0 m\u1ef9 ph\u1ea9m"},"content":{"rendered":"

Cyclomethicon \u2013 silicon v\u00f2ng d\u1ec5 bay h\u01a1i cho kem v\u00e0 m\u1ef9 ph\u1ea9m<\/h1>\n

Cyclomethicon<\/strong> l\u00e0 siloxan v\u00f2ng methyl h\u00f3a ho\u00e0n to\u00e0n, \u0111\u01a1n v\u1ecb l\u1eb7p [\u2013(CH3<\/sub>)2<\/sub>SiO\u2013]n<\/sub> v\u1edbi n = 4, 5, 6 (D4, D5, D6) ho\u1eb7c h\u1ed7n h\u1ee3p. Nh\u1edd d\u1ec5 bay h\u01a1i<\/strong> v\u00e0 nhi\u1ec7t bay h\u01a1i th\u1ea5p, cyclomethicon cho c\u1ea3m gi\u00e1c “kh\u00f4” khi thoa l\u00ean da \u2013 \u0111\u00e2y l\u00e0 silicon \u0111\u01b0\u1ee3c d\u00f9ng nhi\u1ec1u nh\u1ea5t trong m\u1ef9 ph\u1ea9m, \u0111\u1ed3ng th\u1eddi l\u00e0 t\u00e1 d\u01b0\u1ee3c cho kem d\u00f9ng ngo\u00e0i.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\nDimethylcyclopolysiloxane, cyclopolydimethylsiloxane; Dow Corning 245, 246, 345 Fluid<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n69430-24-6<\/td>\n<\/tr>\n
C\u00f4ng th\u1ee9c<\/td>\n[\u2013(CH3<\/sub>)2<\/sub>SiO\u2013]n<\/sub>, n = 4, 5 ho\u1eb7c 6<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nCh\u1ea5t l\u00e0m m\u1ec1m, ch\u1ea5t gi\u1eef \u1ea9m, ch\u1ea5t t\u0103ng \u0111\u1ed9 nh\u1edbt<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u1ea2nh minh h\u1ecda v\u1ebd ph\u00e2n t\u1eed v\u00f2ng 5 \u0111\u01a1n v\u1ecb (D5, decamethylcyclopentasiloxan).<\/em><\/p>\n

Applications<\/h2>\n
    \n
  • Ch\u1ebf ph\u1ea9m d\u00f9ng ngo\u00e0i v\u00e0 m\u1ef9 ph\u1ea9m, \u0111\u1eb7c bi\u1ec7t kem n\u01b0\u1edbc\/d\u1ea7u (N\/D).<\/li>\n
  • D\u00f9ng trong m\u1ef9 ph\u1ea9m \u1edf 0,1\u201350% t\u1eeb cu\u1ed1i th\u1eadp ni\u00ean 1970.<\/li>\n
  • Bay h\u01a1i nhanh, kh\u1ea3 n\u0103ng h\u00f2a tan nh\u1eb9 \u2013 t\u1ea1o c\u1ea3m gi\u00e1c kh\u00f4 tho\u00e1ng, kh\u00f4ng nh\u1eddn; d\u1eabn c\u00e1c th\u00e0nh ph\u1ea7n kh\u00e1c r\u1ed3i bay \u0111i.<\/li>\n
  • T\u1eebng \u0111\u01b0\u1ee3c d\u00f9ng trong b\u1ed9t pha u\u1ed1ng.<\/li>\n<\/ul>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • Ch\u1ea5t l\u1ecfng trong, kh\u00f4ng m\u00e0u, kh\u00f4ng v\u1ecb, d\u1ec5 bay h\u01a1i.<\/li>\n
    • Tan trong ethanol 95%, isopropyl myristat, isopropyl palmitat, d\u1ea7u kho\u00e1ng, vaselin (\u1edf 80 \u00b0C); h\u1ea7u nh\u01b0 kh\u00f4ng tan trong glycerin, propylen glycol, n\u01b0\u1edbc.<\/li>\n<\/ul>\n\n\n\n\n\n\n\n
      C\u1ea5p<\/th>\nChi\u1ebft su\u1ea5t (25 \u00b0C)<\/th>\nS\u1ee9c c\u0103ng b\u1ec1 m\u1eb7t (mN\/m)<\/th>\nT\u1ef7 tr\u1ecdng (25 \u00b0C)<\/th>\n\u0110\u1ed9 nh\u1edbt \u0111\u1ed9ng h\u1ecdc (mm\u00b2\/s)<\/th>\n<\/tr>\n<\/thead>\n
      Dow Corning 245 Fluid<\/td>\n1,397<\/td>\n18,0<\/td>\n0,95<\/td>\n4,0<\/td>\n<\/tr>\n
      Dow Corning 246 Fluid<\/td>\n1,402<\/td>\n18,8<\/td>\n0,96<\/td>\n6,8<\/td>\n<\/tr>\n
      Dow Corning 345 Fluid<\/td>\n1,398<\/td>\n20,8<\/td>\n0,957<\/td>\n6,0<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

      S\u1ee9c c\u0103ng b\u1ec1 m\u1eb7t r\u1ea5t th\u1ea5p gi\u00fap cyclomethicon tr\u1ea3i \u0111\u1ec1u tr\u00ean da.<\/p>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n

      B\u1ea3o qu\u1ea3n trong bao b\u00ec k\u00edn kh\u00ed (tr\u00e1nh bay h\u01a1i), n\u01a1i kh\u00f4 m\u00e1t.<\/p>\n

      S\u1ea3n xu\u1ea5t<\/h2>\n

      Ch\u01b0ng c\u1ea5t polydimethylsiloxan th\u00f4.<\/p>\n

      An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n

      \u0110\u01b0\u1ee3c xem l\u00e0 t\u01b0\u01a1ng \u0111\u1ed1i kh\u00f4ng \u0111\u1ed9c, kh\u00f4ng k\u00edch \u1ee9ng; nghi\u00ean c\u1ee9u tr\u00ean \u0111\u1ed9ng v\u1eadt v\u00e0 ng\u01b0\u1eddi cho th\u1ea5y kh\u00f4ng k\u00edch \u1ee9ng v\u00e0 kh\u00f4ng h\u1ea5p thu qua da; \u0111\u01b0\u1eddng u\u1ed1ng h\u1ea5p thu r\u1ea5t \u00edt. Thao t\u00e1c theo bi\u1ec7n ph\u00e1p th\u00f4ng th\u01b0\u1eddng. L\u01b0u \u00fd: sau n\u0103m 2006, m\u1ed9t s\u1ed1 siloxan v\u00f2ng (D4, D5, D6) \u0111\u00e3 b\u1ecb h\u1ea1n ch\u1ebf trong s\u1ea3n ph\u1ea9m r\u1eeda tr\u00f4i t\u1ea1i ch\u00e2u \u00c2u v\u00ec l\u00fd do m\u00f4i tr\u01b0\u1eddng \u2013 c\u1ea7n ki\u1ec3m tra quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh.<\/p>\n

      T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
        \n
      • C\u00f3 trong FDA Inactive Ingredients Guide (b\u1ed9t pha u\u1ed1ng).<\/li>\n
      • C\u00f3 trong thu\u1ed1c kh\u00f4ng ti\u00eam \u0111\u01b0\u1ee3c c\u1ea5p ph\u00e9p t\u1ea1i Anh; c\u00f3 trong danh m\u1ee5c t\u00e1 d\u01b0\u1ee3c \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn c\u1ee7a Canada.<\/li>\n
      • C\u00f3 chuy\u00ean lu\u1eadn trong USP-NF.<\/li>\n<\/ul>\n

        Ch\u1ea5t li\u00ean quan:<\/strong> dimethicon, simethicon.<\/p>\n

        Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

        N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Cyclomethicone<\/em> trong:
        \nRowe R.C., Sheskey P.J., Owen S.C. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 5.
        \nPharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2006.
        \nB\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

        \u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n

        L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2006.
        \nTi\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh
        \nhi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

        Cyclomethicon \u2013 silicon v\u00f2ng d\u1ec5 bay h\u01a1i cho kem v\u00e0 m\u1ef9 ph\u1ea9m Cyclomethicon l\u00e0 siloxan v\u00f2ng methyl h\u00f3a ho\u00e0n to\u00e0n, \u0111\u01a1n v\u1ecb l\u1eb7p [\u2013(CH3)2SiO\u2013]n v\u1edbi n = 4, 5, 6 (D4, D5, D6) ho\u1eb7c h\u1ed7n h\u1ee3p. Nh\u1edd d\u1ec5 bay h\u01a1i v\u00e0 nhi\u1ec7t bay h\u01a1i th\u1ea5p, cyclomethicon cho c\u1ea3m gi\u00e1c “kh\u00f4” khi thoa l\u00ean da \u2013 […]<\/p>","protected":false},"author":1,"featured_media":2279,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-2280","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":[],"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/cyclomethicon.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/cyclomethicon-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/cyclomethicon-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/cyclomethicon-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/cyclomethicon-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/cyclomethicon.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/cyclomethicon.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/cyclomethicon-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Cyclomethicon \u2013 silicon v\u00f2ng d\u1ec5 bay h\u01a1i cho kem v\u00e0 m\u1ef9 ph\u1ea9m Cyclomethicon l\u00e0 siloxan v\u00f2ng methyl h\u00f3a ho\u00e0n to\u00e0n, \u0111\u01a1n v\u1ecb l\u1eb7p [\u2013(CH3)2SiO\u2013]n v\u1edbi n = 4, 5, 6 (D4, D5, D6) ho\u1eb7c h\u1ed7n h\u1ee3p. Nh\u1edd d\u1ec5 bay h\u01a1i v\u00e0 nhi\u1ec7t bay h\u01a1i th\u1ea5p, cyclomethicon cho c\u1ea3m gi\u00e1c “kh\u00f4” khi thoa l\u00ean da \u2013…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2280","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=2280"}],"version-history":[{"count":0,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2280\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2279"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=2280"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=2280"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=2280"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}