{"id":2258,"date":"2026-09-27T11:05:15","date_gmt":"2026-09-27T04:05:15","guid":{"rendered":"https:\/\/cpc1.vn\/cloroxylenol-pcmx\/"},"modified":"2026-09-29T11:56:49","modified_gmt":"2026-09-29T04:56:49","slug":"cloroxylenol-pcmx","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/cloroxylenol-pcmx\/","title":{"rendered":"Cloroxylenol (PCMX) \u2013 ch\u1ea5t b\u1ea3o qu\u1ea3n v\u00e0 s\u00e1t khu\u1ea9n g\u1ed1c phenol"},"content":{"rendered":"

Cloroxylenol (PCMX) \u2013 ch\u1ea5t b\u1ea3o qu\u1ea3n v\u00e0 s\u00e1t khu\u1ea9n g\u1ed1c phenol<\/h1>\n

Cloroxylenol<\/strong> (PCMX, parachlorometaxylenol) l\u00e0 d\u1eabn ch\u1ea5t phenol clo h\u00f3a, th\u00e0nh ph\u1ea7n c\u1ee7a nhi\u1ec1u dung d\u1ecbch s\u00e1t khu\u1ea9n da quen thu\u1ed9c. V\u1edbi vai tr\u00f2 t\u00e1 d\u01b0\u1ee3c, cloroxylenol \u0111\u01b0\u1ee3c d\u00f9ng \u1edf n\u1ed3ng \u0111\u1ed9 th\u1ea5p l\u00e0m ch\u1ea5t b\u1ea3o qu\u1ea3n cho kem, thu\u1ed1c m\u1ee1 v\u00e0 thu\u1ed1c nh\u1ecf tai.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\nPCMX, 4-chloro-3,5-dimethylphenol, p-chloro-m-xylenol, Nipacide PX<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n88-04-0<\/td>\n<\/tr>\n
C\u00f4ng th\u1ee9c \u2013 KLPT<\/td>\nC8<\/sub>H9<\/sub>ClO \u2013 156,61<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nCh\u1ea5t b\u1ea3o qu\u1ea3n kh\u00e1ng khu\u1ea9n, ch\u1ea5t s\u00e1t khu\u1ea9n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u1ee8ng d\u1ee5ng v\u00e0 n\u1ed3ng \u0111\u1ed9<\/h2>\n\n\n\n\n\n\n\n
M\u1ee5c \u0111\u00edch<\/th>\nN\u1ed3ng \u0111\u1ed9 (%)<\/th>\n<\/tr>\n<\/thead>\n
Ch\u1ea5t b\u1ea3o qu\u1ea3n cho ch\u1ebf ph\u1ea9m nh\u1ecf tai v\u00e0 d\u00f9ng ngo\u00e0i<\/td>\n0,1\u20130,8<\/td>\n<\/tr>\n
B\u1ed9t s\u00e1t khu\u1ea9n<\/td>\n0,5<\/td>\n<\/tr>\n
Dung d\u1ecbch s\u00e1t khu\u1ea9n<\/td>\n2,5\u20135,0<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Cloroxylenol c\u0169ng c\u00f3 m\u1eb7t trong nhi\u1ec1u m\u1ef9 ph\u1ea9m.<\/p>\n

Ho\u1ea1t t\u00ednh kh\u00e1ng khu\u1ea9n<\/h2>\n
    \n
  • T\u00e1c d\u1ee5ng t\u1ed1t tr\u00ean vi khu\u1ea9n Gram d\u01b0\u01a1ng, y\u1ebfu h\u01a1n tr\u00ean Gram \u00e2m; kh\u00f4ng t\u00e1c d\u1ee5ng tr\u00ean b\u00e0o t\u1eed.<\/li>\n
  • Th\u00eam ch\u1ea5t t\u1ea1o ph\u1ee9c nh\u01b0 acid edetic l\u00e0m t\u0103ng t\u00e1c d\u1ee5ng tr\u00ean tr\u1ef1c khu\u1ea9n Gram \u00e2m.<\/li>\n
  • pH dung d\u1ecbch \u00edt \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn ho\u1ea1t t\u00ednh (kh\u00e1c nhi\u1ec1u ch\u1ea5t b\u1ea3o qu\u1ea3n kh\u00e1c).<\/li>\n
  • Ho\u1ea1t t\u00ednh c\u00f3 th\u1ec3 gi\u1ea3m do th\u1ea5t tho\u00e1t v\u00e0o bao b\u00ec ho\u1eb7c t\u01b0\u01a1ng t\u00e1c v\u1edbi t\u00e1 d\u01b0\u1ee3c nh\u01b0 ch\u1ea5t di\u1ec7n ho\u1ea1t kh\u00f4ng ion h\u00f3a.<\/li>\n<\/ul>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • Tinh th\u1ec3 ho\u1eb7c b\u1ed9t k\u1ebft tinh tr\u1eafng ho\u1eb7c m\u00e0u kem, m\u00f9i phenol \u0111\u1eb7c tr\u01b0ng; bay theo h\u01a1i n\u01b0\u1edbc.<\/li>\n
    • N\u00f3ng ch\u1ea3y 114\u2013116 \u00b0C; s\u00f4i 246 \u00b0C.<\/li>\n
    • D\u1ec5 tan trong ethanol 95%; tan trong ether, terpen, d\u1ea7u b\u00e9o v\u00e0 dung d\u1ecbch hydroxyd ki\u1ec1m; r\u1ea5t kh\u00f3 tan trong n\u01b0\u1edbc.<\/li>\n<\/ul>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n

      B\u1ec1n \u1edf nhi\u1ec7t \u0111\u1ed9 ph\u00f2ng nh\u01b0ng bay theo h\u01a1i n\u01b0\u1edbc. Tr\u00e1nh ti\u1ebfp x\u00fac cao su t\u1ef1 nhi\u00ean. Dung d\u1ecbch n\u01b0\u1edbc d\u1ec5 nhi\u1ec5m vi sinh \u2013 c\u1ea7n bi\u1ec7n ph\u00e1p tr\u00e1nh nhi\u1ec5m khi b\u1ea3o qu\u1ea3n ho\u1eb7c pha lo\u00e3ng. \u0110\u1ef1ng trong bao b\u00ec polyethylen, th\u00e9p th\u01b0\u1eddng ho\u1eb7c th\u00e9p kh\u00f4ng g\u1ec9, \u0111\u1eady k\u00edn, n\u01a1i kh\u00f4 m\u00e1t.<\/p>\n

      T\u01b0\u01a1ng k\u1ef5<\/h2>\n

      T\u01b0\u01a1ng k\u1ef5 v\u1edbi ch\u1ea5t di\u1ec7n ho\u1ea1t kh\u00f4ng ion h\u00f3a v\u00e0 methylcellulose.<\/p>\n

      S\u1ea3n xu\u1ea5t<\/h2>\n

      Cho 3,5-dimethylphenol ph\u1ea3n \u1ee9ng v\u1edbi clo ho\u1eb7c sulfuryl clorid (SO2<\/sub>Cl2<\/sub>).<\/p>\n

      An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n

      V\u1edbi vai tr\u00f2 t\u00e1 d\u01b0\u1ee3c, cloroxylenol \u0111\u01b0\u1ee3c xem l\u00e0 t\u01b0\u01a1ng \u0111\u1ed1i kh\u00f4ng \u0111\u1ed9c, kh\u00f4ng k\u00edch \u1ee9ng, d\u00f9 c\u00f3 b\u00e1o c\u00e1o d\u1ecb \u1ee9ng da. \u0110\u01b0\u1eddng u\u1ed1ng c\u00f3 \u0111\u1ed9c t\u00ednh nh\u1eb9; \u0111\u00e3 c\u00f3 tr\u01b0\u1eddng h\u1ee3p t\u1ef1 \u0111\u1ea7u \u0111\u1ed9c n\u1eb7ng ho\u1eb7c t\u1eed vong do u\u1ed1ng dung d\u1ecbch s\u00e1t khu\u1ea9n ch\u1ee9a cloroxylenol. Ch\u1ea5t n\u00e0y k\u00edch \u1ee9ng m\u1eaft \u2013 \u0111eo k\u00ednh b\u1ea3o h\u1ed9; ph\u00e2n h\u1ee7y nhi\u1ec7t t\u1ea1o kh\u00f3i \u0111\u1ed9c.<\/p>\n

      T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
        \n
      • C\u00f3 trong FDA Inactive Ingredients Guide (ch\u1ebf ph\u1ea9m nh\u1ecf tai; kem v\u00e0 nh\u0169 t\u01b0\u01a1ng d\u00f9ng ngo\u00e0i).<\/li>\n
      • C\u00f3 trong thu\u1ed1c kh\u00f4ng d\u00f9ng \u0111\u01b0\u1eddng ti\u00eam \u0111\u01b0\u1ee3c c\u1ea5p ph\u00e9p t\u1ea1i Anh.<\/li>\n
      • C\u00f3 chuy\u00ean lu\u1eadn trong BP v\u00e0 USP.<\/li>\n<\/ul>\n

        Ch\u1ea5t li\u00ean quan:<\/strong> clorocresol.<\/p>\n

        Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

        N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Chloroxylenol<\/em> trong: Rowe R.C., Sheskey P.J., Owen S.C. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 5. Pharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2006. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

        \u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n

        L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2006. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

        Cloroxylenol (PCMX) \u2013 ch\u1ea5t b\u1ea3o qu\u1ea3n v\u00e0 s\u00e1t khu\u1ea9n g\u1ed1c phenol Cloroxylenol (PCMX, parachlorometaxylenol) l\u00e0 d\u1eabn ch\u1ea5t phenol clo h\u00f3a, th\u00e0nh ph\u1ea7n c\u1ee7a nhi\u1ec1u dung d\u1ecbch s\u00e1t khu\u1ea9n da quen thu\u1ed9c. V\u1edbi vai tr\u00f2 t\u00e1 d\u01b0\u1ee3c, cloroxylenol \u0111\u01b0\u1ee3c d\u00f9ng \u1edf n\u1ed3ng \u0111\u1ed9 th\u1ea5p l\u00e0m ch\u1ea5t b\u1ea3o qu\u1ea3n cho kem, thu\u1ed1c m\u1ee1 v\u00e0 thu\u1ed1c nh\u1ecf tai. […]<\/p>\n","protected":false},"author":1,"featured_media":2257,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-2258","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/cloroxylenol-pcmx.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/cloroxylenol-pcmx-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/cloroxylenol-pcmx-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/cloroxylenol-pcmx-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/cloroxylenol-pcmx-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/cloroxylenol-pcmx.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/cloroxylenol-pcmx.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/cloroxylenol-pcmx-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Cloroxylenol (PCMX) \u2013 ch\u1ea5t b\u1ea3o qu\u1ea3n v\u00e0 s\u00e1t khu\u1ea9n g\u1ed1c phenol Cloroxylenol (PCMX, parachlorometaxylenol) l\u00e0 d\u1eabn ch\u1ea5t phenol clo h\u00f3a, th\u00e0nh ph\u1ea7n c\u1ee7a nhi\u1ec1u dung d\u1ecbch s\u00e1t khu\u1ea9n da quen thu\u1ed9c. V\u1edbi vai tr\u00f2 t\u00e1 d\u01b0\u1ee3c, cloroxylenol \u0111\u01b0\u1ee3c d\u00f9ng \u1edf n\u1ed3ng \u0111\u1ed9 th\u1ea5p l\u00e0m ch\u1ea5t b\u1ea3o qu\u1ea3n cho kem, thu\u1ed1c m\u1ee1 v\u00e0 thu\u1ed1c nh\u1ecf tai.…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2258","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=2258"}],"version-history":[{"count":2,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2258\/revisions"}],"predecessor-version":[{"id":3771,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2258\/revisions\/3771"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2257"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=2258"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=2258"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=2258"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}