{"id":2252,"date":"2026-09-27T11:04:07","date_gmt":"2026-09-27T04:04:07","guid":{"rendered":"https:\/\/cpc1.vn\/clorodifluoroethan-hcfc-142b\/"},"modified":"2026-09-28T21:07:10","modified_gmt":"2026-09-28T14:07:10","slug":"clorodifluoroethan-hcfc-142b","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/clorodifluoroethan-hcfc-142b\/","title":{"rendered":"Clorodifluoroethan (HCFC 142b) \u2013 kh\u00ed \u0111\u1ea9y aerosol \u0111\u00e3 ng\u1eebng d\u00f9ng trong d\u01b0\u1ee3c"},"content":{"rendered":"

Clorodifluoroethan (HCFC 142b) \u2013 kh\u00ed \u0111\u1ea9y aerosol \u0111\u00e3 ng\u1eebng d\u00f9ng trong d\u01b0\u1ee3c<\/h1>\n

Clorodifluoroethan<\/strong> (HCFC 142b, propellant 142b) l\u00e0 kh\u00ed \u0111\u1ea9y aerosol thu\u1ed9c nh\u00f3m hydroclorofluorocarbon, tr\u01b0\u1edbc \u0111\u00e2y<\/strong> \u0111\u01b0\u1ee3c d\u00f9ng trong thu\u1ed1c d\u00f9ng ngo\u00e0i d\u1ea1ng aerosol. Hi\u1ec7n nay ch\u1ea5t n\u00e0y kh\u00f4ng c\u00f2n \u0111\u01b0\u1ee3c ph\u00e9p d\u00f9ng trong d\u01b0\u1ee3c ph\u1ea9m<\/strong> do g\u00e2y h\u1ea1i m\u00f4i tr\u01b0\u1eddng (suy gi\u1ea3m t\u1ea7ng ozon). B\u00e0i vi\u1ebft mang t\u00ednh tham kh\u1ea3o l\u1ecbch s\u1eed v\u00e0 k\u1ef9 thu\u1eadt.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\n1,1-Difluoro-1-chloroethane, HCFC 142b, P-142b, propellant\/refrigerant 142b; Dymel 142b, Genetron 142b, Solkane 142b<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n75-68-3<\/td>\n<\/tr>\n
C\u00f4ng th\u1ee9c \u2013 KLPT<\/td>\nC2<\/sub>H3<\/sub>ClF2<\/sub> \u2013 100,50<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nKh\u00ed \u0111\u1ea9y aerosol<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u1ee8ng d\u1ee5ng (tr\u01b0\u1edbc \u0111\u00e2y)<\/h2>\n
    \n
  • Kh\u00ed \u0111\u1ea9y cho aerosol d\u00f9ng ngo\u00e0i; th\u01b0\u1eddng ph\u1ed1i h\u1ee3p difluoroethan \u0111\u1ec3 t\u1ea1o h\u1ed7n h\u1ee3p kh\u00ed \u0111\u1ea9y c\u00f3 t\u1ef7 tr\u1ecdng b\u1eb1ng 1.<\/li>\n
  • Ph\u1ed1i h\u1ee3p v\u1edbi clorodifluoromethan v\u00e0 kh\u00ed \u0111\u1ea9y hydrocarbon.<\/li>\n
  • C\u00f3 th\u1ec3 d\u00f9ng l\u00e0m ch\u1ea5t d\u1eabn cho h\u1ec7 ph\u00e2n t\u00e1n v\u00e0 nh\u0169 t\u01b0\u01a1ng.<\/li>\n<\/ul>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • Kh\u00ed h\u00f3a l\u1ecfng: \u1edf nhi\u1ec7t \u0111\u1ed9 ph\u00f2ng t\u1ed3n t\u1ea1i d\u1ea1ng l\u1ecfng d\u01b0\u1edbi \u00e1p su\u1ea5t h\u01a1i c\u1ee7a ch\u00ednh n\u00f3, bay h\u01a1i th\u00e0nh kh\u00ed \u1edf \u00e1p su\u1ea5t th\u01b0\u1eddng. Ch\u1ea5t l\u1ecfng g\u1ea7n nh\u01b0 kh\u00f4ng m\u00f9i, kh\u00f4ng m\u00e0u; kh\u00f4ng \u0103n m\u00f2n, kh\u00f4ng k\u00edch \u1ee9ng.<\/li>\n
    • Nhi\u1ec7t \u0111\u1ed9 s\u00f4i \u22129,8 \u00b0C; nhi\u1ec7t \u0111\u1ed9 t\u1edbi h\u1ea1n 137,1 \u00b0C.<\/li>\n
    • T\u1ef7 tr\u1ecdng l\u1ecfng 1,11 g\/cm\u00b3 (25 \u00b0C); \u00e1p su\u1ea5t h\u01a1i 339 kPa \u1edf 25 \u00b0C.<\/li>\n
    • D\u1ec5 ch\u00e1y<\/strong>: gi\u1edbi h\u1ea1n ch\u00e1y 6,2\u201317,9% th\u1ec3 t\u00edch trong kh\u00f4ng kh\u00ed.<\/li>\n
    • Tan 1\/715 trong n\u01b0\u1edbc (20 \u00b0C).<\/li>\n<\/ul>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n

      Kh\u00f4ng ph\u1ea3n \u1ee9ng, b\u1ec1n; b\u1ea3o qu\u1ea3n trong b\u00ecnh kim lo\u1ea1i, n\u01a1i kh\u00f4 m\u00e1t.<\/p>\n

      T\u01b0\u01a1ng k\u1ef5<\/h2>\n

      T\u01b0\u01a1ng h\u1ee3p v\u1edbi c\u00e1c th\u00e0nh ph\u1ea7n th\u01b0\u1eddng g\u1eb7p trong aerosol d\u01b0\u1ee3c ph\u1ea9m; c\u00f3 th\u1ec3 ph\u1ea3n \u1ee9ng m\u1ea1nh v\u1edbi ch\u1ea5t oxy h\u00f3a.<\/p>\n

      An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n

      \u0110\u01b0\u1ee3c xem l\u00e0 g\u1ea7n nh\u01b0 kh\u00f4ng \u0111\u1ed9c, kh\u00f4ng k\u00edch \u1ee9ng, nh\u01b0ng c\u1ed1 \u00fd h\u00edt l\u01b0\u1ee3ng l\u1edbn kh\u00ed \u0111\u1ea9y c\u00f3 th\u1ec3 g\u00e2y t\u1eed vong. Nh\u00e3n aerosol ph\u1ea3i c\u00f3 c\u1ea3nh b\u00e1o tr\u00e1nh h\u00edt, tr\u00e1nh m\u1eaft v\u00e0 ni\u00eam m\u1ea1c, b\u00ecnh ch\u1ecbu \u00e1p su\u1ea5t \u2013 kh\u00f4ng ch\u1ecdc th\u1ee7ng, kh\u00f4ng \u0111\u1ed1t, kh\u00f4ng \u0111\u1ec3 n\u01a1i tr\u00ean 49 \u00b0C, \u0111\u1ec3 xa t\u1ea7m tay tr\u1ebb em; t\u1ea1i M\u1ef9 c\u00f2n c\u1ea3nh b\u00e1o v\u1ec1 h\u1ea1i t\u1ea7ng ozon.<\/p>\n

      Thao t\u00e1c theo quy \u0111\u1ecbnh v\u1edbi kh\u00ed h\u00f3a l\u1ecfng; d\u00f9ng k\u00ednh, g\u0103ng tay, qu\u1ea7n \u00e1o b\u1ea3o h\u1ed9, n\u01a1i th\u00f4ng gi\u00f3. H\u01a1i n\u1eb7ng h\u01a1n kh\u00f4ng kh\u00ed v\u00e0 kh\u00f4ng duy tr\u00ec s\u1ef1 s\u1ed1ng \u2013 khi v\u1ec7 sinh b\u1ed3n ch\u1ee9a l\u1edbn ph\u1ea3i c\u1ea5p \u0111\u1ee7 oxy cho c\u00f4ng nh\u00e2n. Khi ph\u00e2n h\u1ee7y nhi\u1ec7t t\u1ea1o kh\u00f3i \u0111\u1ed9c.<\/p>\n

      Ch\u1ea5t li\u00ean quan<\/h2>\n

      Clorodifluoromethan<\/strong> (HCFC 22, propellant 22; CHClF2<\/sub>, KLPT 86,47; CAS 75-45-6): nhi\u1ec7t \u0111\u1ed9 s\u00f4i \u221240,8 \u00b0C, \u00e1p su\u1ea5t h\u01a1i 1041 kPa \u1edf 25 \u00b0C; t\u1eebng d\u00f9ng l\u00e0m kh\u00ed \u0111\u1ea9y aerosol d\u00f9ng ngo\u00e0i; gi\u1edbi h\u1ea1n ph\u01a1i nhi\u1ec5m 3590 mg\/m\u00b3 (1000 ppm, 8 gi\u1edd).<\/p>\n

      C\u00e1c kh\u00ed \u0111\u1ea9y thay th\u1ebf hi\u1ec7n nay trong d\u01b0\u1ee3c ph\u1ea9m l\u00e0 hydrofluoroalkan (HFA 134a, HFA 227) v\u00e0 hydrocarbon.<\/p>\n

      Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

      N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Chlorodifluoroethane (HCFC)<\/em> trong: Rowe R.C., Sheskey P.J., Owen S.C. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 5. Pharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2006. B\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

      \u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n

      L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2006. Ti\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

      Clorodifluoroethan (HCFC 142b) \u2013 kh\u00ed \u0111\u1ea9y aerosol \u0111\u00e3 ng\u1eebng d\u00f9ng trong d\u01b0\u1ee3c Clorodifluoroethan (HCFC 142b, propellant 142b) l\u00e0 kh\u00ed \u0111\u1ea9y aerosol thu\u1ed9c nh\u00f3m hydroclorofluorocarbon, tr\u01b0\u1edbc \u0111\u00e2y \u0111\u01b0\u1ee3c d\u00f9ng trong thu\u1ed1c d\u00f9ng ngo\u00e0i d\u1ea1ng aerosol. Hi\u1ec7n nay ch\u1ea5t n\u00e0y kh\u00f4ng c\u00f2n \u0111\u01b0\u1ee3c ph\u00e9p d\u00f9ng trong d\u01b0\u1ee3c ph\u1ea9m do g\u00e2y h\u1ea1i m\u00f4i tr\u01b0\u1eddng (suy gi\u1ea3m t\u1ea7ng ozon). […]<\/p>","protected":false},"author":1,"featured_media":2251,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-2252","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":[],"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/clorodifluoroethan-hcfc-142b.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/clorodifluoroethan-hcfc-142b-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/clorodifluoroethan-hcfc-142b-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/clorodifluoroethan-hcfc-142b-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/clorodifluoroethan-hcfc-142b-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/clorodifluoroethan-hcfc-142b.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/clorodifluoroethan-hcfc-142b.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/clorodifluoroethan-hcfc-142b-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Clorodifluoroethan (HCFC 142b) \u2013 kh\u00ed \u0111\u1ea9y aerosol \u0111\u00e3 ng\u1eebng d\u00f9ng trong d\u01b0\u1ee3c Clorodifluoroethan (HCFC 142b, propellant 142b) l\u00e0 kh\u00ed \u0111\u1ea9y aerosol thu\u1ed9c nh\u00f3m hydroclorofluorocarbon, tr\u01b0\u1edbc \u0111\u00e2y \u0111\u01b0\u1ee3c d\u00f9ng trong thu\u1ed1c d\u00f9ng ngo\u00e0i d\u1ea1ng aerosol. Hi\u1ec7n nay ch\u1ea5t n\u00e0y kh\u00f4ng c\u00f2n \u0111\u01b0\u1ee3c ph\u00e9p d\u00f9ng trong d\u01b0\u1ee3c ph\u1ea9m do g\u00e2y h\u1ea1i m\u00f4i tr\u01b0\u1eddng (suy gi\u1ea3m t\u1ea7ng ozon).…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2252","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=2252"}],"version-history":[{"count":1,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2252\/revisions"}],"predecessor-version":[{"id":3175,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2252\/revisions\/3175"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2251"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=2252"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=2252"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=2252"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}