{"id":2238,"date":"2026-09-27T10:59:24","date_gmt":"2026-09-27T03:59:24","guid":{"rendered":"https:\/\/cpc1.vn\/alcol-cetylic\/"},"modified":"2026-09-28T14:34:03","modified_gmt":"2026-09-28T07:34:03","slug":"alcol-cetylic","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/alcol-cetylic\/","title":{"rendered":"Alcol cetylic (Cetyl Alcohol) \u2013 t\u00e1 d\u01b0\u1ee3c l\u00e0m \u0111\u1eb7c, l\u00e0m m\u1ec1m, nh\u0169 h\u00f3a"},"content":{"rendered":"

Alcol cetylic (Cetyl Alcohol) \u2013 t\u00e1 d\u01b0\u1ee3c l\u00e0m \u0111\u1eb7c, l\u00e0m m\u1ec1m, nh\u0169 h\u00f3a<\/h1>\n

Alcol cetylic<\/strong> (cetyl alcohol, 1-hexadecanol, palmityl alcohol) l\u00e0 alcol b\u00e9o C16 d\u1ea1ng s\u00e1p, \u0111\u01b0\u1ee3c d\u00f9ng r\u1ed9ng r\u00e3i trong kem, lotion, thu\u1ed1c m\u1ee1, thu\u1ed1c \u0111\u1eb7t v\u00e0 c\u1ea3 d\u1ea1ng r\u1eafn gi\u1ea3i ph\u00f3ng bi\u1ebfn \u0111\u1ed5i. Alcol cetylic \u0111\u01b0\u1ee3c m\u1ec7nh danh l\u00e0 “ch\u1ea5t c\u1ea3i thi\u1ec7n \u0111\u1ed9 \u0111\u1eb7c” (consistency improver, bodying agent) c\u1ee7a nh\u0169 t\u01b0\u01a1ng.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\n1-Hexadecanol, n-hexadecyl alcohol, palmityl alcohol, ethal; t\u00ean th\u01b0\u01a1ng m\u1ea1i: Crodacol C70\/C90\/C95, Lanette 16, Kessco CA, Lipocol C, Tego Alkanol 16<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n36653-82-4<\/td>\n<\/tr>\n
C\u00f4ng th\u1ee9c \u2013 KLPT<\/td>\nC16<\/sub>H34<\/sub>O \u2013 242,44 (ch\u1ea5t tinh khi\u1ebft)<\/td>\n<\/tr>\n
Th\u00e0nh ph\u1ea7n<\/td>\nUSP-NF: \u2265 90,0% alcol cetylic, ph\u1ea7n c\u00f2n l\u1ea1i ch\u1ee7 y\u1ebfu alcol t\u01b0\u01a1ng t\u1ef1. Nhi\u1ec1u lo\u1ea1i th\u01b0\u01a1ng m\u1ea1i ch\u1ee9a 60\u201370% cetylic v\u00e0 20\u201330% stearylic<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nT\u00e1 d\u01b0\u1ee3c bao, ch\u1ea5t nh\u0169 h\u00f3a, ch\u1ea5t l\u00e0m c\u1ee9ng<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u1ee8ng d\u1ee5ng v\u00e0 n\u1ed3ng \u0111\u1ed9<\/h2>\n\n\n\n\n\n\n\n\n
Vai tr\u00f2<\/th>\nN\u1ed3ng \u0111\u1ed9 (%)<\/th>\n<\/tr>\n<\/thead>\n
Ch\u1ea5t l\u00e0m m\u1ec1m<\/td>\n2\u20135<\/td>\n<\/tr>\n
Ch\u1ea5t nh\u0169 h\u00f3a<\/td>\n2\u20135<\/td>\n<\/tr>\n
Ch\u1ea5t l\u00e0m c\u1ee9ng<\/td>\n2\u201310<\/td>\n<\/tr>\n
H\u00fat n\u01b0\u1edbc<\/td>\n5<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
    \n
  • Thu\u1ed1c \u0111\u1eb7t<\/strong>: n\u00e2ng \u0111i\u1ec3m ch\u1ea3y c\u1ee7a t\u00e1 d\u01b0\u1ee3c n\u1ec1n.<\/li>\n
  • D\u1ea1ng r\u1eafn gi\u1ea3i ph\u00f3ng bi\u1ebfn \u0111\u1ed5i<\/strong>: t\u1ea1o m\u00e0ng bao th\u1ea5m.<\/li>\n
  • Kem, lotion, thu\u1ed1c m\u1ee1<\/strong>: l\u00e0m m\u1ec1m (th\u1ea5m v\u00e0 l\u01b0u l\u1ea1i \u1edf th\u01b0\u1ee3ng b\u00ec, cho c\u1ea3m gi\u00e1c “m\u1ecbn nh\u01b0 nhung”), h\u00fat n\u01b0\u1edbc, nh\u0169 h\u00f3a; t\u0103ng \u0111\u1ed9 \u1ed5n \u0111\u1ecbnh, c\u1ea3i thi\u1ec7n c\u1ea5u tr\u00fac, t\u0103ng \u0111\u1ed9 \u0111\u1eb7c.<\/li>\n
  • Nh\u0169 t\u01b0\u01a1ng N\/D<\/strong>: h\u1ed7n h\u1ee3p vaselin : alcol cetylic (19:1) h\u00fat \u0111\u01b0\u1ee3c 40\u201350% kh\u1ed1i l\u01b0\u1ee3ng n\u01b0\u1edbc; alcol cetylic l\u00e0 ch\u1ea5t nh\u0169 h\u00f3a N\/D y\u1ebfu, gi\u00fap gi\u1ea3m l\u01b0\u1ee3ng ch\u1ea5t nh\u0169 h\u00f3a kh\u00e1c.<\/li>\n
  • Nh\u0169 t\u01b0\u01a1ng D\/N<\/strong>: k\u1ebft h\u1ee3p v\u1edbi ch\u1ea5t nh\u0169 h\u00f3a tan trong n\u01b0\u1edbc t\u1ea1o m\u00e0ng \u0111\u01a1n ph\u00e2n t\u1eed kh\u00edt \u1edf b\u1ec1 m\u1eb7t d\u1ea7u\u2013n\u01b0\u1edbc, ng\u0103n gi\u1ecdt k\u1ebft t\u1ee5; l\u01b0\u1ee3ng d\u01b0 t\u1ea1o pha li\u00ean t\u1ee5c nh\u1edbt \u0111\u00e0n h\u1ed3i, l\u00e0m nh\u0169 t\u01b0\u01a1ng c\u00f3 th\u1ec3 ch\u1ea5t b\u00e1n r\u1eafn.<\/li>\n<\/ul>\n

    L\u01b0u \u00fd: alcol cetylic tinh khi\u1ebft ho\u1eb7c c\u1ea5p d\u01b0\u1ee3c \u0111i\u1ec3n c\u00f3 th\u1ec3 kh\u00f4ng t\u1ea1o nh\u0169 t\u01b0\u01a1ng b\u00e1n r\u1eafn \u1ed5n \u0111\u1ecbnh nh\u01b0 c\u00e1c lo\u1ea1i c\u00f3 l\u1eabn \u0111\u00e1ng k\u1ec3 alcol t\u01b0\u01a1ng t\u1ef1 (nh\u01b0 alcol stearylic).<\/p>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • V\u1ea3y, h\u1ea1t, kh\u1ed1i s\u00e1p tr\u1eafng; m\u00f9i nh\u1eb9 \u0111\u1eb7c tr\u01b0ng, v\u1ecb nh\u1ea1t.<\/li>\n
    • N\u00f3ng ch\u1ea3y 45\u201352 \u00b0C (49 \u00b0C v\u1edbi ch\u1ea5t tinh khi\u1ebft); s\u00f4i 316\u2013344 \u00b0C; \u0111i\u1ec3m ch\u1edbp ch\u00e1y 165 \u00b0C; t\u1ef7 tr\u1ecdng 0,908 g\/cm\u00b3.<\/li>\n
    • D\u1ec5 tan trong ethanol 95% v\u00e0 ether (t\u0103ng theo nhi\u1ec7t \u0111\u1ed9); h\u1ea7u nh\u01b0 kh\u00f4ng tan trong n\u01b0\u1edbc; khi n\u00f3ng ch\u1ea3y tr\u1ed9n l\u1eabn v\u1edbi m\u1ee1, parafin l\u1ecfng v\u00e0 r\u1eafn, isopropyl myristat.<\/li>\n<\/ul>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n

      B\u1ec1n v\u1edbi acid, ki\u1ec1m, \u00e1nh s\u00e1ng, kh\u00f4ng kh\u00ed; kh\u00f4ng b\u1ecb \u00f4i. B\u1ea3o qu\u1ea3n trong bao b\u00ec k\u00edn, n\u01a1i kh\u00f4 m\u00e1t.<\/p>\n

      T\u01b0\u01a1ng k\u1ef5<\/h2>\n

      T\u01b0\u01a1ng k\u1ef5 v\u1edbi ch\u1ea5t oxy h\u00f3a m\u1ea1nh. Alcol cetylic l\u00e0m h\u1ea1 \u0111i\u1ec3m ch\u1ea3y c\u1ee7a ibuprofen, g\u00e2y d\u00ednh khi bao phim tinh th\u1ec3 ibuprofen.<\/p>\n

      S\u1ea3n xu\u1ea5t<\/h2>\n

      Ester h\u00f3a v\u00e0 hydrogenolysis acid b\u00e9o, ho\u1eb7c hydro h\u00f3a x\u00fac t\u00e1c triglycerid t\u1eeb d\u1ea7u d\u1eeba hay m\u1ee1 \u0111\u1ed9ng v\u1eadt; tinh ch\u1ebf b\u1eb1ng k\u1ebft tinh v\u00e0 ch\u01b0ng c\u1ea5t.<\/p>\n

      An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n

      D\u00f9ng ch\u1ee7 y\u1ebfu trong ch\u1ebf ph\u1ea9m d\u00f9ng ngo\u00e0i, ngo\u00e0i ra trong thu\u1ed1c u\u1ed1ng v\u00e0 tr\u1ef1c tr\u00e0ng. \u0110\u00e3 ghi nh\u1eadn ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn mu\u1ed9n \u1edf ng\u01b0\u1eddi b\u1ecb vi\u00eam da \u1ee9 tr\u1ec7 v\u00e0 m\u1eabn c\u1ea3m ch\u00e9o v\u1edbi alcol cetostearylic, lanolin, alcol stearylic \u2013 c\u00f3 th\u1ec3 do t\u1ea1p ch\u1ea5t, v\u00ec lo\u1ea1i tinh ch\u1ebf cao (99,5%) ch\u01b0a ghi nh\u1eadn qu\u00e1 m\u1eabn. D\u00f9ng k\u00ednh v\u00e0 g\u0103ng tay khi thao t\u00e1c.<\/p>\n

      T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
        \n
      • C\u00f3 trong FDA Inactive Ingredients Guide (nh\u1ecf m\u1eaft, vi\u00ean nang, vi\u00ean n\u00e9n u\u1ed1ng, nh\u1ecf tai, tr\u1ef1c tr\u00e0ng, kh\u00ed dung, kem, nh\u0169 t\u01b0\u01a1ng, thu\u1ed1c m\u1ee1, dung d\u1ecbch d\u00f9ng ngo\u00e0i, \u00e2m \u0111\u1ea1o).<\/li>\n
      • C\u00f3 trong thu\u1ed1c kh\u00f4ng ti\u00eam \u0111\u01b0\u1ee3c c\u1ea5p ph\u00e9p t\u1ea1i Anh; c\u00f3 trong danh m\u1ee5c t\u00e1 d\u01b0\u1ee3c \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn c\u1ee7a Canada.<\/li>\n
      • C\u00f3 chuy\u00ean lu\u1eadn trong JP, Ph.Eur. v\u00e0 USP-NF.<\/li>\n<\/ul>\n

        Ch\u1ea5t li\u00ean quan:<\/strong> alcol cetostearylic, alcol stearylic.<\/p>\n

        Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

        N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Cetyl Alcohol<\/em> trong:
        \nRowe R.C., Sheskey P.J., Owen S.C. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 5.
        \nPharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2006.
        \nB\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

        \u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n

        L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2006.
        \nTi\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh
        \nhi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

        Alcol cetylic (Cetyl Alcohol) \u2013 t\u00e1 d\u01b0\u1ee3c l\u00e0m \u0111\u1eb7c, l\u00e0m m\u1ec1m, nh\u0169 h\u00f3a Alcol cetylic (cetyl alcohol, 1-hexadecanol, palmityl alcohol) l\u00e0 alcol b\u00e9o C16 d\u1ea1ng s\u00e1p, \u0111\u01b0\u1ee3c d\u00f9ng r\u1ed9ng r\u00e3i trong kem, lotion, thu\u1ed1c m\u1ee1, thu\u1ed1c \u0111\u1eb7t v\u00e0 c\u1ea3 d\u1ea1ng r\u1eafn gi\u1ea3i ph\u00f3ng bi\u1ebfn \u0111\u1ed5i. Alcol cetylic \u0111\u01b0\u1ee3c m\u1ec7nh danh l\u00e0 “ch\u1ea5t c\u1ea3i thi\u1ec7n \u0111\u1ed9 […]<\/p>","protected":false},"author":1,"featured_media":2237,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-2238","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":[],"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/alcol-cetylic.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/alcol-cetylic-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/alcol-cetylic-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/alcol-cetylic-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/alcol-cetylic-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/alcol-cetylic.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/alcol-cetylic.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/alcol-cetylic-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Alcol cetylic (Cetyl Alcohol) \u2013 t\u00e1 d\u01b0\u1ee3c l\u00e0m \u0111\u1eb7c, l\u00e0m m\u1ec1m, nh\u0169 h\u00f3a Alcol cetylic (cetyl alcohol, 1-hexadecanol, palmityl alcohol) l\u00e0 alcol b\u00e9o C16 d\u1ea1ng s\u00e1p, \u0111\u01b0\u1ee3c d\u00f9ng r\u1ed9ng r\u00e3i trong kem, lotion, thu\u1ed1c m\u1ee1, thu\u1ed1c \u0111\u1eb7t v\u00e0 c\u1ea3 d\u1ea1ng r\u1eafn gi\u1ea3i ph\u00f3ng bi\u1ebfn \u0111\u1ed5i. Alcol cetylic \u0111\u01b0\u1ee3c m\u1ec7nh danh l\u00e0 “ch\u1ea5t c\u1ea3i thi\u1ec7n \u0111\u1ed9…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2238","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=2238"}],"version-history":[{"count":1,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2238\/revisions"}],"predecessor-version":[{"id":2807,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2238\/revisions\/2807"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2237"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=2238"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=2238"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=2238"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}