{"id":2234,"date":"2026-09-27T10:58:10","date_gmt":"2026-09-27T03:58:10","guid":{"rendered":"https:\/\/cpc1.vn\/alcol-cetostearylic\/"},"modified":"2026-09-28T14:34:05","modified_gmt":"2026-09-28T07:34:05","slug":"alcol-cetostearylic","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/alcol-cetostearylic\/","title":{"rendered":"Alcol cetostearylic (Cetearyl Alcohol) \u2013 t\u00e1 d\u01b0\u1ee3c l\u00e0m \u0111\u1eb7c, \u0111\u1ed3ng nh\u0169 h\u00f3a"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Alcol cetostearylic (Cetearyl Alcohol) \u2013 t\u00e1 d\u01b0\u1ee3c l\u00e0m \u0111\u1eb7c, \u0111\u1ed3ng nh\u0169 h\u00f3a<\/h1>\n<p><strong>Alcol cetostearylic<\/strong> (cetostearyl alcohol, cetearyl alcohol) l\u00e0 h\u1ed7n h\u1ee3p alcol b\u00e9o r\u1eafn, ch\u1ee7 y\u1ebfu g\u1ed3m <strong>alcol stearylic (C18)<\/strong> v\u00e0 <strong>alcol cetylic (C16)<\/strong>. \u0110\u00e2y l\u00e0 t\u00e1 d\u01b0\u1ee3c n\u1ec1n quen thu\u1ed9c c\u1ee7a kem v\u00e0 lotion: l\u00e0m \u0111\u1eb7c, t\u1ea1o &#8220;th\u00e2n&#8221; cho nh\u0169 t\u01b0\u01a1ng v\u00e0 \u0111\u00f3ng vai tr\u00f2 \u0111\u1ed3ng nh\u0169 h\u00f3a.<\/p>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean kh\u00e1c<\/td>\n<td>Cetearyl alcohol; t\u00ean th\u01b0\u01a1ng m\u1ea1i: Lanette O, Crodacol CS90, Tego Alkanol 1618, Tego Alkanol 6855<\/td>\n<\/tr>\n<tr>\n<td>S\u1ed1 CAS<\/td>\n<td>67762-27-0 v\u00e0 8005-44-5<\/td>\n<\/tr>\n<tr>\n<td>Th\u00e0nh ph\u1ea7n<\/td>\n<td>Th\u01b0\u1eddng 50\u201370% alcol stearylic v\u00e0 20\u201335% alcol cetylic (t\u1ed5ng \u2265 90%); ph\u1ea7n c\u00f2n l\u1ea1i ch\u1ee7 y\u1ebfu alcol myristylic<\/td>\n<\/tr>\n<tr>\n<td>Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\n<td>Ch\u1ea5t l\u00e0m m\u1ec1m, ch\u1ea5t nh\u0169 h\u00f3a, ch\u1ea5t t\u0103ng \u0111\u1ed9 nh\u1edbt<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Ph.Eur. c\u00f2n c\u00f3 hai lo\u1ea1i <strong>alcol cetostearylic nh\u0169 h\u00f3a<\/strong> ch\u1ee9a \u00edt nh\u1ea5t 7% ch\u1ea5t di\u1ec7n ho\u1ea1t: lo\u1ea1i A ch\u1ee9a natri cetostearyl sulfat, lo\u1ea1i B ch\u1ee9a natri lauryl sulfat.<\/p>\n<h2>\u1ee8ng d\u1ee5ng trong b\u00e0o ch\u1ebf<\/h2>\n<ul>\n<li>T\u0103ng \u0111\u1ed9 nh\u1edbt, t\u1ea1o th\u00e2n cho nh\u0169 t\u01b0\u01a1ng d\u1ea7u\/n\u01b0\u1edbc v\u00e0 n\u01b0\u1edbc\/d\u1ea7u trong ch\u1ebf ph\u1ea9m d\u00f9ng ngo\u00e0i v\u00e0 m\u1ef9 ph\u1ea9m.<\/li>\n<li>\u1ed4n \u0111\u1ecbnh nh\u0169 t\u01b0\u01a1ng v\u00e0 \u0111\u1ed3ng nh\u0169 h\u00f3a \u2013 gi\u1ea3m l\u01b0\u1ee3ng ch\u1ea5t di\u1ec7n ho\u1ea1t c\u1ea7n thi\u1ebft.<\/li>\n<li>Kem kh\u00f4ng ch\u1ee9a n\u01b0\u1edbc v\u00e0 d\u1ea1ng th\u1ecfi (stick).<\/li>\n<li>\u0110\u01b0\u1ee3c nghi\u00ean c\u1ee9u \u0111\u1ec3 l\u00e0m ch\u1eadm h\u00f2a tan ho\u1ea1t ch\u1ea5t tan trong n\u01b0\u1edbc.<\/li>\n<li>Khi ph\u1ed1i h\u1ee3p ch\u1ea5t di\u1ec7n ho\u1ea1t, t\u1ea1o nh\u0169 t\u01b0\u01a1ng vi c\u1ea5u tr\u00fac ph\u1ee9c t\u1ea1p (tinh th\u1ec3 l\u1ecfng, c\u1ea5u tr\u00fac phi\u1ebfn, pha gel) \u2013 n\u1ec1n t\u1ea3ng \u0111\u1ed9 \u0111\u1eb7c v\u00e0 \u0111\u1ed9 \u1ed5n \u0111\u1ecbnh c\u1ee7a kem.<\/li>\n<\/ul>\n<h2>M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n<ul>\n<li>Kh\u1ed1i s\u00e1p tr\u01a1n m\u00e0u tr\u1eafng ho\u1eb7c kem, ho\u1eb7c v\u1ea3y\/h\u1ea1t g\u1ea7n tr\u1eafng; m\u00f9i ng\u1ecdt nh\u1eb9 \u0111\u1eb7c tr\u01b0ng. Khi n\u00f3ng ch\u1ea3y th\u00e0nh ch\u1ea5t l\u1ecfng trong, kh\u00f4ng m\u00e0u ho\u1eb7c v\u00e0ng nh\u1ea1t.<\/li>\n<li>Tan trong ethanol 95%, ether v\u00e0 d\u1ea7u; h\u1ea7u nh\u01b0 kh\u00f4ng tan trong n\u01b0\u1edbc.<\/li>\n<\/ul>\n<h2>\u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n<p>B\u1ec1n trong \u0111i\u1ec1u ki\u1ec7n b\u1ea3o qu\u1ea3n th\u00f4ng th\u01b0\u1eddng; \u0111\u1ef1ng trong bao b\u00ec k\u00edn, n\u01a1i kh\u00f4 m\u00e1t.<\/p>\n<h2>T\u01b0\u01a1ng k\u1ef5<\/h2>\n<p>T\u01b0\u01a1ng k\u1ef5 v\u1edbi ch\u1ea5t oxy h\u00f3a m\u1ea1nh v\u00e0 mu\u1ed1i kim lo\u1ea1i.<\/p>\n<h2>S\u1ea3n xu\u1ea5t<\/h2>\n<p>Kh\u1eed c\u00e1c acid b\u00e9o t\u01b0\u01a1ng \u1ee9ng t\u1eeb ngu\u1ed3n th\u1ef1c v\u1eadt ho\u1eb7c \u0111\u1ed9ng v\u1eadt, ho\u1eb7c \u0111i\u1ec1u ch\u1ebf tr\u1ef1c ti\u1ebfp t\u1eeb ngu\u1ed3n hydrocarbon. Th\u00e0nh ph\u1ea7n c\u00e1c alcol ph\u1ee5 (m\u1ea1ch th\u1eb3ng, m\u1ea1ch nh\u00e1nh) thay \u0111\u1ed5i nhi\u1ec1u theo ngu\u1ed3n g\u1ed1c \u0111\u1ed9ng v\u1eadt, th\u1ef1c v\u1eadt hay t\u1ed5ng h\u1ee3p \u2013 \u0111i\u1ec1u n\u00e0y c\u00f3 th\u1ec3 l\u00e0m kh\u00e1c bi\u1ec7t \u0111\u1ed9 \u0111\u1eb7c v\u00e0 \u0111\u1ed9 \u1ed5n \u0111\u1ecbnh nh\u0169 t\u01b0\u01a1ng gi\u1eefa c\u00e1c nh\u00e0 cung c\u1ea5p.<\/p>\n<h2>An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n<p>D\u00f9ng ch\u1ee7 y\u1ebfu trong ch\u1ebf ph\u1ea9m d\u00f9ng ngo\u00e0i v\u00e0 m\u1ef9 ph\u1ea9m; \u0111\u01b0\u1ee3c xem l\u00e0 kh\u00f4ng \u0111\u1ed9c, h\u1ea7u nh\u01b0 kh\u00f4ng k\u00edch \u1ee9ng, tuy \u0111\u00e3 c\u00f3 b\u00e1o c\u00e1o m\u1eabn c\u1ea3m v\u1edbi alcol cetostearylic, cetylic v\u00e0 stearylic. D\u00f9ng k\u00ednh v\u00e0 g\u0103ng tay khi thao t\u00e1c; ch\u1ea5t n\u00e0y ch\u00e1y \u0111\u01b0\u1ee3c, khi ch\u00e1y c\u00f3 th\u1ec3 sinh kh\u00ed CO.<\/p>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n<ul>\n<li>T\u1ea1i M\u1ef9 \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn l\u00e0 ph\u1ee5 gia th\u1ef1c ph\u1ea9m gi\u00e1n ti\u1ebfp, ch\u1ea5t k\u1ebft d\u00ednh v\u00e0 th\u00e0nh ph\u1ea7n l\u1edbp ph\u1ee7 bao b\u00ec.<\/li>\n<li>C\u00f3 trong FDA Inactive Ingredients Guide (vi\u00ean n\u00e9n u\u1ed1ng; nh\u0169 t\u01b0\u01a1ng, lotion, thu\u1ed1c m\u1ee1 d\u00f9ng ngo\u00e0i; vi\u00ean \u0111\u1eb7t \u00e2m \u0111\u1ea1o).<\/li>\n<li>C\u00f3 trong thu\u1ed1c kh\u00f4ng ti\u00eam \u0111\u01b0\u1ee3c c\u1ea5p ph\u00e9p t\u1ea1i Anh; c\u00f3 trong danh m\u1ee5c t\u00e1 d\u01b0\u1ee3c \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn c\u1ee7a Canada.<\/li>\n<li>C\u00f3 chuy\u00ean lu\u1eadn trong Ph.Eur. v\u00e0 USP-NF.<\/li>\n<\/ul>\n<p><strong>Ch\u1ea5t li\u00ean quan:<\/strong> s\u00e1p nh\u0169 h\u00f3a anion, alcol cetylic, alcol stearylic, natri lauryl sulfat.<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<p>N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn <em>Cetostearyl Alcohol<\/em> trong:<br \/>\nRowe R.C., Sheskey P.J., Owen S.C. (ch\u1ee7 bi\u00ean). <em>Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 5.<br \/>\nPharmaceutical Press (London) &amp; American Pharmacists Association (Washington DC), 2006.<br \/>\nB\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n<p><em>\u1ea2nh minh h\u1ecda: thi\u1ebft k\u1ebf c\u1ee7a CPC1.<\/em><\/p>\n<p><em>L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2006.<br \/>\nTi\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh<br \/>\nhi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Alcol cetostearylic (Cetearyl Alcohol) \u2013 t\u00e1 d\u01b0\u1ee3c l\u00e0m \u0111\u1eb7c, \u0111\u1ed3ng nh\u0169 h\u00f3a Alcol cetostearylic (cetostearyl alcohol, cetearyl alcohol) l\u00e0 h\u1ed7n h\u1ee3p alcol b\u00e9o r\u1eafn, ch\u1ee7 y\u1ebfu g\u1ed3m alcol stearylic (C18) v\u00e0 alcol cetylic (C16). \u0110\u00e2y l\u00e0 t\u00e1 d\u01b0\u1ee3c n\u1ec1n quen thu\u1ed9c c\u1ee7a kem v\u00e0 lotion: l\u00e0m \u0111\u1eb7c, t\u1ea1o &#8220;th\u00e2n&#8221; cho nh\u0169 t\u01b0\u01a1ng v\u00e0 \u0111\u00f3ng vai [&hellip;]<\/p>","protected":false},"author":1,"featured_media":2233,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-2234","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":[],"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/alcol-cetostearylic.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/alcol-cetostearylic-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/alcol-cetostearylic-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/alcol-cetostearylic-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/alcol-cetostearylic-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/alcol-cetostearylic.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/alcol-cetostearylic.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/alcol-cetostearylic-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Alcol cetostearylic (Cetearyl Alcohol) \u2013 t\u00e1 d\u01b0\u1ee3c l\u00e0m \u0111\u1eb7c, \u0111\u1ed3ng nh\u0169 h\u00f3a Alcol cetostearylic (cetostearyl alcohol, cetearyl alcohol) l\u00e0 h\u1ed7n h\u1ee3p alcol b\u00e9o r\u1eafn, ch\u1ee7 y\u1ebfu g\u1ed3m alcol stearylic (C18) v\u00e0 alcol cetylic (C16). \u0110\u00e2y l\u00e0 t\u00e1 d\u01b0\u1ee3c n\u1ec1n quen thu\u1ed9c c\u1ee7a kem v\u00e0 lotion: l\u00e0m \u0111\u1eb7c, t\u1ea1o &#8220;th\u00e2n&#8221; cho nh\u0169 t\u01b0\u01a1ng v\u00e0 \u0111\u00f3ng vai&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2234","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=2234"}],"version-history":[{"count":1,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2234\/revisions"}],"predecessor-version":[{"id":2808,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2234\/revisions\/2808"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2233"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=2234"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=2234"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=2234"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}