{"id":2232,"date":"2026-09-27T10:57:19","date_gmt":"2026-09-27T03:57:19","guid":{"rendered":"https:\/\/cpc1.vn\/cellulose-acetat\/"},"modified":"2026-09-27T10:57:19","modified_gmt":"2026-09-27T03:57:19","slug":"cellulose-acetat","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/cellulose-acetat\/","title":{"rendered":"Cellulose acetat \u2013 m\u00e0ng b\u00e1n th\u1ea5m cho vi\u00ean b\u01a1m th\u1ea9m th\u1ea5u, gi\u1ea3i ph\u00f3ng k\u00e9o d\u00e0i"},"content":{"rendered":"

Cellulose acetat \u2013 m\u00e0ng b\u00e1n th\u1ea5m cho vi\u00ean b\u01a1m th\u1ea9m th\u1ea5u, gi\u1ea3i ph\u00f3ng k\u00e9o d\u00e0i<\/h1>\n

Cellulose acetat<\/strong> l\u00e0 cellulose trong \u0111\u00f3 m\u1ed9t ph\u1ea7n ho\u1eb7c to\u00e0n b\u1ed9 nh\u00f3m hydroxyl \u0111\u01b0\u1ee3c acetyl h\u00f3a. Trong b\u00e0o ch\u1ebf, cellulose acetat n\u1ed5i ti\u1ebfng nh\u1ea5t v\u1edbi vai tr\u00f2 m\u00e0ng b\u00e1n th\u1ea5m c\u1ee7a vi\u00ean b\u01a1m th\u1ea9m th\u1ea5u<\/strong> (osmotic pump), ngo\u00e0i ra d\u00f9ng \u0111\u1ec3 che v\u1ecb v\u00e0 l\u00e0m c\u1ed1t gi\u1ea3i ph\u00f3ng k\u00e9o d\u00e0i.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\nAcetyl cellulose, cellulose diacetate, cellulose triacetate<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n9004-35-7 (cellulose acetat); 9035-69-2 (diacetat); 9012-09-3 (triacetat)<\/td>\n<\/tr>\n
C\u1ea5u t\u1ea1o<\/td>\nC\u00f3 nhi\u1ec1u m\u1ee9c acetyl v\u00e0 \u0111\u1ed9 d\u00e0i m\u1ea1ch kh\u00e1c nhau, v\u00ec v\u1eady KLPT dao \u0111\u1ed9ng r\u1ed9ng<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nT\u00e1 d\u01b0\u1ee3c bao, t\u00e1 d\u01b0\u1ee3c gi\u1ea3i ph\u00f3ng k\u00e9o d\u00e0i, t\u00e1 d\u01b0\u1ee3c \u0111\u1ed9n vi\u00ean n\u00e9n v\u00e0 vi\u00ean nang<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u1ee8ng d\u1ee5ng trong b\u00e0o ch\u1ebf<\/h2>\n
    \n
  • M\u00e0ng bao b\u00e1n th\u1ea5m<\/strong> cho vi\u00ean n\u00e9n (\u0111\u1eb7c bi\u1ec7t vi\u00ean b\u01a1m th\u1ea9m th\u1ea5u) v\u00e0 d\u1ea1ng c\u1ea5y \u2013 cho gi\u1ea3i ph\u00f3ng k\u00e9o d\u00e0i c\u00f3 ki\u1ec3m so\u00e1t. Ph\u1ed1i h\u1ee3p v\u1edbi v\u1eadt li\u1ec7u kh\u00e1c, m\u00e0ng cellulose acetat c\u00f2n cho gi\u1ea3i ph\u00f3ng k\u00e9o d\u00e0i m\u00e0 kh\u00f4ng c\u1ea7n khoan l\u1ed7 tr\u00ean m\u00e0ng.<\/li>\n
  • Che v\u1ecb<\/strong>: bao h\u1ea1t ho\u1ea1t ch\u1ea5t (v\u00ed d\u1ee5 h\u1ea1t paracetamol) tr\u01b0\u1edbc khi d\u1eadp vi\u00ean nhai.<\/li>\n
  • C\u1ed1t d\u1eadp th\u1eb3ng gi\u1ea3i ph\u00f3ng k\u00e9o d\u00e0i<\/strong>: \u0111i\u1ec1u ch\u1ec9nh b\u1eb1ng t\u1ef7 l\u1ec7 ho\u1ea1t ch\u1ea5t\/cellulose acetat v\u00e0 ch\u1ea5t h\u00f3a d\u1ebbo; \u00edt ph\u1ee5 thu\u1ed9c KLPT v\u00e0 c\u1ee1 h\u1ea1t cellulose acetat.<\/li>\n
  • Vi h\u1ea1t gi\u1ea3i ph\u00f3ng ki\u1ec3m so\u00e1t; m\u00e0ng trong h\u1ec7 \u0111\u01b0a thu\u1ed1c qua da.<\/li>\n<\/ul>\n

    M\u1ed9t s\u1ed1 c\u1ea5p th\u01b0\u01a1ng m\u1ea1i (Eastman)<\/h2>\n\n\n\n\n\n\n\n\n\n
    C\u1ea5p<\/th>\nAcetyl (%)<\/th>\nHydroxyl (%)<\/th>\n\u0110\u1ed9 nh\u1edbt (mPa\u00b7s)<\/th>\nKho\u1ea3ng n\u00f3ng ch\u1ea3y (\u00b0C)<\/th>\nMn<\/sub><\/th>\n<\/tr>\n<\/thead>\n
    CA-320S<\/td>\n32,0<\/td>\n8,7<\/td>\n210<\/td>\n230\u2013250<\/td>\n38.000<\/td>\n<\/tr>\n
    CA-398-3<\/td>\n39,8<\/td>\n3,5<\/td>\n11,4<\/td>\n230\u2013250<\/td>\n30.000<\/td>\n<\/tr>\n
    CA-398-10NF<\/td>\n39,8<\/td>\n3,5<\/td>\n38<\/td>\n230\u2013250<\/td>\n40.000<\/td>\n<\/tr>\n
    CA-398-30<\/td>\n39,7<\/td>\n3,5<\/td>\n114<\/td>\n230\u2013250<\/td>\n50.000<\/td>\n<\/tr>\n
    CA-435-75<\/td>\n43,5<\/td>\n0,9<\/td>\n\u2014<\/td>\n280\u2013300<\/td>\n122.000<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • B\u1ed9t, vi\u00ean nh\u1ecf tr\u01a1n ch\u1ea3y ho\u1eb7c v\u1ea3y m\u00e0u tr\u1eafng \u0111\u1ebfn tr\u1eafng ng\u00e0; kh\u00f4ng v\u1ecb, kh\u00f4ng m\u00f9i ho\u1eb7c tho\u1ea3ng m\u00f9i acid acetic.<\/li>\n
    • T\u1ef7 tr\u1ecdng bi\u1ec3u ki\u1ebfn d\u1ea1ng b\u1ed9t kho\u1ea3ng 0,4 g\/cm\u00b3; nhi\u1ec7t \u0111\u1ed9 h\u00f3a th\u1ee7y tinh 170\u2013190 \u00b0C; kho\u1ea3ng n\u00f3ng ch\u1ea3y 230\u2013300 \u00b0C.<\/li>\n
    • \u0110\u1ed9 tan ph\u1ee5 thu\u1ed9c m\u1ea1nh m\u1ee9c acetyl: n\u00f3i chung tan trong h\u1ed7n h\u1ee3p aceton\u2013n\u01b0\u1edbc, diclomethan\u2013ethanol, dimethylformamid, dioxan; lo\u1ea1i acetyl cao k\u00e9n dung m\u00f4i h\u01a1n.<\/li>\n
    • Dung d\u1ecbch 10% trong dung m\u00f4i h\u1eefu c\u01a1 c\u00f3 \u0111\u1ed9 nh\u1edbt 10\u2013230 mPa\u00b7s t\u00f9y c\u1ea5p.<\/li>\n<\/ul>\n

      T\u01b0\u01a1ng k\u1ef5<\/h2>\n

      T\u01b0\u01a1ng k\u1ef5 v\u1edbi ch\u1ea5t acid ho\u1eb7c ki\u1ec1m m\u1ea1nh. T\u01b0\u01a1ng h\u1ee3p v\u1edbi c\u00e1c ch\u1ea5t h\u00f3a d\u1ebbo: diethyl phthalat, polyethylen glycol, triacetin, triethyl citrat.<\/p>\n

      S\u1ea3n xu\u1ea5t<\/h2>\n

      X\u1eed l\u00fd cellulose tinh khi\u1ebft cao v\u1edbi anhydrid acetic, x\u00fac t\u00e1c acid.<\/p>\n

      M\u1eb9o pha ch\u1ebf<\/h2>\n

      Khi pha dung d\u1ecbch, lu\u00f4n cho cellulose acetat v\u00e0o dung m\u00f4i, kh\u00f4ng l\u00e0m ng\u01b0\u1ee3c l\u1ea1i.<\/p>\n

      An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n

      D\u00f9ng r\u1ed9ng r\u00e3i trong thu\u1ed1c u\u1ed1ng, \u0111\u01b0\u1ee3c xem l\u00e0 kh\u00f4ng \u0111\u1ed9c, kh\u00f4ng k\u00edch \u1ee9ng. B\u1ee5i c\u00f3 th\u1ec3 k\u00edch \u1ee9ng m\u1eaft \u2013 \u0111eo k\u00ednh. Nh\u01b0 ph\u1ea7n l\u1edbn b\u1ed9t h\u1eefu c\u01a1, c\u00f3 nguy c\u01a1 n\u1ed5 b\u1ee5i; cellulose acetat l\u00e0 v\u1eadt li\u1ec7u ch\u00e1y \u0111\u01b0\u1ee3c.<\/p>\n

      T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
        \n
      • C\u00f3 trong FDA Inactive Ingredients Guide (vi\u00ean n\u00e9n u\u1ed1ng); c\u00f3 trong danh m\u1ee5c t\u00e1 d\u01b0\u1ee3c \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn c\u1ee7a Canada.<\/li>\n
      • C\u00f3 chuy\u00ean lu\u1eadn trong BP, Ph.Eur. v\u00e0 USP-NF.<\/li>\n<\/ul>\n

        Ch\u1ea5t li\u00ean quan:<\/strong> cellulose acetat phthalat.<\/p>\n

        Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

        N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Cellulose Acetate<\/em> trong:
        \nRowe R.C., Sheskey P.J., Owen S.C. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 5.
        \nPharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2006.
        \nB\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

        \u1ea2nh minh h\u1ecda: thi\u1ebft k\u1ebf c\u1ee7a CPC1.<\/em><\/p>\n

        L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2006.
        \nTi\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh
        \nhi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

        Cellulose acetat \u2013 m\u00e0ng b\u00e1n th\u1ea5m cho vi\u00ean b\u01a1m th\u1ea9m th\u1ea5u, gi\u1ea3i ph\u00f3ng k\u00e9o d\u00e0i Cellulose acetat l\u00e0 cellulose trong \u0111\u00f3 m\u1ed9t ph\u1ea7n ho\u1eb7c to\u00e0n b\u1ed9 nh\u00f3m hydroxyl \u0111\u01b0\u1ee3c acetyl h\u00f3a. Trong b\u00e0o ch\u1ebf, cellulose acetat n\u1ed5i ti\u1ebfng nh\u1ea5t v\u1edbi vai tr\u00f2 m\u00e0ng b\u00e1n th\u1ea5m c\u1ee7a vi\u00ean b\u01a1m th\u1ea9m th\u1ea5u (osmotic pump), ngo\u00e0i ra d\u00f9ng […]<\/p>","protected":false},"author":1,"featured_media":2231,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-2232","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":[],"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/cellulose-acetat.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/cellulose-acetat-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/cellulose-acetat-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/cellulose-acetat-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/cellulose-acetat-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/cellulose-acetat.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/cellulose-acetat.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/cellulose-acetat-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Cellulose acetat \u2013 m\u00e0ng b\u00e1n th\u1ea5m cho vi\u00ean b\u01a1m th\u1ea9m th\u1ea5u, gi\u1ea3i ph\u00f3ng k\u00e9o d\u00e0i Cellulose acetat l\u00e0 cellulose trong \u0111\u00f3 m\u1ed9t ph\u1ea7n ho\u1eb7c to\u00e0n b\u1ed9 nh\u00f3m hydroxyl \u0111\u01b0\u1ee3c acetyl h\u00f3a. Trong b\u00e0o ch\u1ebf, cellulose acetat n\u1ed5i ti\u1ebfng nh\u1ea5t v\u1edbi vai tr\u00f2 m\u00e0ng b\u00e1n th\u1ea5m c\u1ee7a vi\u00ean b\u01a1m th\u1ea9m th\u1ea5u (osmotic pump), ngo\u00e0i ra d\u00f9ng…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2232","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=2232"}],"version-history":[{"count":0,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2232\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2231"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=2232"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=2232"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=2232"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}