{"id":2196,"date":"2026-09-27T10:46:13","date_gmt":"2026-09-27T03:46:13","guid":{"rendered":"https:\/\/cpc1.vn\/calci-carbonat\/"},"modified":"2026-09-28T14:34:17","modified_gmt":"2026-09-28T07:34:17","slug":"calci-carbonat","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/calci-carbonat\/","title":{"rendered":"Calci carbonat (Calcium Carbonate) \u2013 t\u00e1 d\u01b0\u1ee3c \u0111\u1ed9n, ch\u1ea5t \u0111\u1ec7m, ch\u1ea5t l\u00e0m \u0111\u1ee5c"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Calci carbonat (Calcium Carbonate) \u2013 t\u00e1 d\u01b0\u1ee3c \u0111\u1ed9n, ch\u1ea5t \u0111\u1ec7m, ch\u1ea5t l\u00e0m \u0111\u1ee5c<\/h1>\n<p><strong>Calci carbonat<\/strong> (CaCO<sub>3<\/sub>, E170) l\u00e0 mu\u1ed1i v\u00f4 c\u01a1 tr\u1eafng, r\u1ebb, tr\u01a1, \u0111\u01b0\u1ee3c d\u00f9ng ch\u1ee7 y\u1ebfu l\u00e0m <strong>t\u00e1 d\u01b0\u1ee3c \u0111\u1ed9n<\/strong> trong d\u1ea1ng thu\u1ed1c r\u1eafn. Ngo\u00e0i ra calci carbonat c\u00f2n l\u00e0 ch\u1ea5t \u0111\u1ec7m, ch\u1ea5t l\u00e0m \u0111\u1ee5c trong m\u00e0ng bao phim, ch\u1ea5t \u0111\u1ed9n trong bao \u0111\u01b0\u1eddng; \u0111\u1ed3ng th\u1eddi l\u00e0 ph\u1ee5 gia th\u1ef1c ph\u1ea9m v\u00e0 ngu\u1ed3n b\u1ed5 sung calci.<\/p>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean kh\u00e1c<\/td>\n<td>Precipitated chalk, precipitated carbonate of lime, creta preparada, E170; t\u00ean th\u01b0\u01a1ng m\u1ea1i: PharmaCarb, Vivapress Ca, Witcarb, MagGran CC, Micromite<\/td>\n<\/tr>\n<tr>\n<td>S\u1ed1 CAS<\/td>\n<td>471-34-1<\/td>\n<\/tr>\n<tr>\n<td>C\u00f4ng th\u1ee9c \u2013 KLPT<\/td>\n<td>CaCO<sub>3<\/sub> \u2013 100,09<\/td>\n<\/tr>\n<tr>\n<td>Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\n<td>Ch\u1ea5t \u0111\u1ec7m, ch\u1ea5t bao, ch\u1ea5t l\u00e0m \u0111\u1ee5c, t\u00e1 d\u01b0\u1ee3c \u0111\u1ed9n vi\u00ean n\u00e9n v\u00e0 vi\u00ean nang<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>\u1ee8ng d\u1ee5ng trong b\u00e0o ch\u1ebf<\/h2>\n<ul>\n<li><strong>T\u00e1 d\u01b0\u1ee3c \u0111\u1ed9n<\/strong> cho vi\u00ean n\u00e9n, vi\u00ean nang.<\/li>\n<li>N\u1ec1n cho ch\u1ebf ph\u1ea9m nha khoa; ch\u1ea5t \u0111\u1ec7m; ch\u1ea5t h\u1ed7 tr\u1ee3 h\u00f2a tan trong vi\u00ean ph\u00e2n t\u00e1n.<\/li>\n<li>Ch\u1ea5t \u0111\u1ed9n trong quy tr\u00ecnh <strong>bao \u0111\u01b0\u1eddng<\/strong>; ch\u1ea5t l\u00e0m \u0111\u1ee5c trong <strong>bao phim<\/strong>.<\/li>\n<li>C\u00f3 lo\u1ea1i d\u1eadp th\u1eb3ng ch\u1ec9 ch\u1ee9a calci carbonat (Vivapress Ca 740, 800) v\u00e0 lo\u1ea1i \u0111\u1ed3ng x\u1eed l\u00fd v\u1edbi t\u00e1 d\u01b0\u1ee3c kh\u00e1c: 10% tinh b\u1ed9t, 50% sorbitol, 50% saccarose, maltodextrin ho\u1eb7c tinh b\u1ed9t ng\u00f4 ti\u1ec1n gelatin h\u00f3a.<\/li>\n<li>Th\u1ef1c ph\u1ea9m: ph\u1ee5 gia; ngo\u00e0i ra l\u00e0 ho\u1ea1t ch\u1ea5t b\u1ed5 sung calci v\u00e0 kh\u00e1ng acid (c\u00f3 lo\u1ea1i h\u00e0m l\u01b0\u1ee3ng ch\u00ec th\u1ea5p ri\u00eang cho m\u1ee5c \u0111\u00edch n\u00e0y).<\/li>\n<\/ul>\n<h2>M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n<ul>\n<li>B\u1ed9t ho\u1eb7c tinh th\u1ec3 tr\u1eafng, kh\u00f4ng m\u00f9i, kh\u00f4ng v\u1ecb.<\/li>\n<li>pH h\u1ec7 ph\u00e2n t\u00e1n 10%: kho\u1ea3ng 9,0.<\/li>\n<li>T\u1ef7 tr\u1ecdng bi\u1ec3u ki\u1ebfn 0,8 g\/cm\u00b3; t\u1ef7 tr\u1ecdng g\u00f5 1,2 g\/cm\u00b3; b\u1ed9t c\u00f3 t\u00ednh k\u1ebft d\u00ednh, tr\u01a1n ch\u1ea3y k\u00e9m; t\u1ef7 tr\u1ecdng th\u1ef1c 2,7.<\/li>\n<li>Ph\u00e2n h\u1ee7y \u1edf 825 \u00b0C; chi\u1ebft su\u1ea5t 1,59; \u0111\u1ed9 c\u1ee9ng Mohs kho\u1ea3ng 3.<\/li>\n<li>H\u1ea7u nh\u01b0 kh\u00f4ng tan trong n\u01b0\u1edbc v\u00e0 ethanol; \u0111\u1ed9 tan trong n\u01b0\u1edbc t\u0103ng khi c\u00f3 mu\u1ed1i amoni ho\u1eb7c CO<sub>2<\/sub>, gi\u1ea3m khi c\u00f3 hydroxyd ki\u1ec1m.<\/li>\n<\/ul>\n<h2>\u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n<p>B\u1ec1n; b\u1ea3o qu\u1ea3n trong bao b\u00ec k\u00edn, n\u01a1i kh\u00f4 m\u00e1t.<\/p>\n<h2>T\u01b0\u01a1ng k\u1ef5<\/h2>\n<ul>\n<li>T\u01b0\u01a1ng k\u1ef5 v\u1edbi acid (gi\u1ea3i ph\u00f3ng CO<sub>2<\/sub>) v\u00e0 mu\u1ed1i amoni.<\/li>\n<li>Trong vi\u00ean ch\u1ee9a aspirin v\u00e0 c\u00e1c ch\u1ea5t t\u01b0\u01a1ng t\u1ef1, v\u1ebft s\u1eaft trong calci carbonat c\u00f3 th\u1ec3 g\u00e2y \u0111\u1ed5i m\u00e0u \u2013 kh\u1eafc ph\u1ee5c b\u1eb1ng ch\u1ea5t t\u1ea1o ph\u1ee9c th\u00edch h\u1ee3p.<\/li>\n<li>D\u00f9ng \u0111\u1ed3ng th\u1eddi c\u00f3 th\u1ec3 c\u1ea3n tr\u1edf h\u1ea5p thu m\u1ed9t s\u1ed1 ho\u1ea1t ch\u1ea5t kh\u00e1c qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a.<\/li>\n<\/ul>\n<h2>S\u1ea3n xu\u1ea5t<\/h2>\n<p>\u0110i\u1ec1u ch\u1ebf b\u1eb1ng ph\u1ea3n \u1ee9ng trao \u0111\u1ed5i gi\u1eefa calci clorid v\u00e0 natri bicarbonat trong n\u01b0\u1edbc \u2013 t\u1ef7 tr\u1ecdng v\u00e0 \u0111\u1ed9 m\u1ecbn ph\u1ee5 thu\u1ed9c n\u1ed3ng \u0111\u1ed9 dung d\u1ecbch (t\u1eeb \u0111\u00f3 c\u00f3 lo\u1ea1i &#8220;n\u1eb7ng&#8221; v\u00e0 &#8220;nh\u1eb9&#8221;). Calci carbonat c\u0169ng \u0111\u01b0\u1ee3c l\u1ea5y t\u1eeb kho\u00e1ng t\u1ef1 nhi\u00ean aragonit, calcit, vaterit.<\/p>\n<h2>An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n<p>D\u00f9ng ch\u1ee7 y\u1ebfu trong thu\u1ed1c u\u1ed1ng, \u0111\u01b0\u1ee3c xem l\u00e0 kh\u00f4ng \u0111\u1ed9c. \u0110\u01b0\u1eddng u\u1ed1ng c\u00f3 th\u1ec3 g\u00e2y t\u00e1o b\u00f3n, \u0111\u1ea7y h\u01a1i; d\u00f9ng l\u01b0\u1ee3ng r\u1ea5t l\u1edbn (4\u201360 g\/ng\u00e0y) c\u00f3 th\u1ec3 g\u00e2y t\u0103ng calci huy\u1ebft ho\u1eb7c suy gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn. B\u1ee5i c\u00f3 th\u1ec3 k\u00edch \u1ee9ng m\u1eaft v\u00e0 h\u00f4 h\u1ea5p \u2013 d\u00f9ng k\u00ednh, g\u0103ng tay, kh\u1ea9u trang, l\u00e0m vi\u1ec7c n\u01a1i th\u00f4ng gi\u00f3. Gi\u1edbi h\u1ea1n ph\u01a1i nhi\u1ec5m t\u1ea1i Anh: 10 mg\/m\u00b3 b\u1ee5i to\u00e0n ph\u1ea7n, 4 mg\/m\u00b3 b\u1ee5i h\u00f4 h\u1ea5p (8 gi\u1edd).<\/p>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n<ul>\n<li>FDA x\u1ebfp nh\u00f3m GRAS; c\u00f3 trong FDA Inactive Ingredients Guide (vi\u00ean nang, vi\u00ean n\u00e9n u\u1ed1ng; dung d\u1ecbch nh\u1ecf tai).<\/li>\n<li>\u0110\u01b0\u1ee3c ch\u1ea5p nh\u1eadn l\u00e0 ph\u1ee5 gia th\u1ef1c ph\u1ea9m t\u1ea1i ch\u00e2u \u00c2u (E170); c\u00f3 trong danh m\u1ee5c t\u00e1 d\u01b0\u1ee3c \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn c\u1ee7a Canada.<\/li>\n<li>C\u00f3 chuy\u00ean lu\u1eadn trong JP, Ph.Eur., USP; c\u00f3 ti\u00eau chu\u1ea9n trong Food Chemicals Codex.<\/li>\n<\/ul>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<p>N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn <em>Calcium Carbonate<\/em> trong:<br \/>\nRowe R.C., Sheskey P.J., Owen S.C. (ch\u1ee7 bi\u00ean). <em>Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 5.<br \/>\nPharmaceutical Press (London) &amp; American Pharmacists Association (Washington DC), 2006.<br \/>\nB\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n<p><em>\u1ea2nh minh h\u1ecda: thi\u1ebft k\u1ebf c\u1ee7a CPC1.<\/em><\/p>\n<p><em>L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2006.<br \/>\nTi\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh<br \/>\nhi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Calci carbonat (Calcium Carbonate) \u2013 t\u00e1 d\u01b0\u1ee3c \u0111\u1ed9n, ch\u1ea5t \u0111\u1ec7m, ch\u1ea5t l\u00e0m \u0111\u1ee5c Calci carbonat (CaCO3, E170) l\u00e0 mu\u1ed1i v\u00f4 c\u01a1 tr\u1eafng, r\u1ebb, tr\u01a1, \u0111\u01b0\u1ee3c d\u00f9ng ch\u1ee7 y\u1ebfu l\u00e0m t\u00e1 d\u01b0\u1ee3c \u0111\u1ed9n trong d\u1ea1ng thu\u1ed1c r\u1eafn. Ngo\u00e0i ra calci carbonat c\u00f2n l\u00e0 ch\u1ea5t \u0111\u1ec7m, ch\u1ea5t l\u00e0m \u0111\u1ee5c trong m\u00e0ng bao phim, ch\u1ea5t \u0111\u1ed9n trong bao [&hellip;]<\/p>","protected":false},"author":1,"featured_media":2195,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-2196","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":[],"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/calci-carbonat.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/calci-carbonat-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/calci-carbonat-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/calci-carbonat-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/calci-carbonat-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/calci-carbonat.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/calci-carbonat.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/calci-carbonat-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Calci carbonat (Calcium Carbonate) \u2013 t\u00e1 d\u01b0\u1ee3c \u0111\u1ed9n, ch\u1ea5t \u0111\u1ec7m, ch\u1ea5t l\u00e0m \u0111\u1ee5c Calci carbonat (CaCO3, E170) l\u00e0 mu\u1ed1i v\u00f4 c\u01a1 tr\u1eafng, r\u1ebb, tr\u01a1, \u0111\u01b0\u1ee3c d\u00f9ng ch\u1ee7 y\u1ebfu l\u00e0m t\u00e1 d\u01b0\u1ee3c \u0111\u1ed9n trong d\u1ea1ng thu\u1ed1c r\u1eafn. Ngo\u00e0i ra calci carbonat c\u00f2n l\u00e0 ch\u1ea5t \u0111\u1ec7m, ch\u1ea5t l\u00e0m \u0111\u1ee5c trong m\u00e0ng bao phim, ch\u1ea5t \u0111\u1ed9n trong bao&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2196","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=2196"}],"version-history":[{"count":1,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2196\/revisions"}],"predecessor-version":[{"id":2815,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2196\/revisions\/2815"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2195"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=2196"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=2196"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=2196"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}