{"id":2182,"date":"2026-09-27T10:42:36","date_gmt":"2026-09-27T03:42:36","guid":{"rendered":"https:\/\/cpc1.vn\/acid-boric\/"},"modified":"2026-09-27T10:42:36","modified_gmt":"2026-09-27T03:42:36","slug":"acid-boric","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/acid-boric\/","title":{"rendered":"Acid boric \u2013 ch\u1ea5t b\u1ea3o qu\u1ea3n, ch\u1ea5t \u0111\u1ec7m trong thu\u1ed1c nh\u1ecf m\u1eaft"},"content":{"rendered":"

Acid boric \u2013 ch\u1ea5t b\u1ea3o qu\u1ea3n, ch\u1ea5t \u0111\u1ec7m trong thu\u1ed1c nh\u1ecf m\u1eaft<\/h1>\n

Acid boric<\/strong> (orthoboric acid, E284) l\u00e0 acid v\u00f4 c\u01a1 y\u1ebfu, c\u00f3 t\u00ednh k\u00ecm khu\u1ea9n nh\u1eb9. Trong b\u00e0o ch\u1ebf, acid boric \u0111\u01b0\u1ee3c d\u00f9ng l\u00e0m ch\u1ea5t b\u1ea3o qu\u1ea3n<\/strong> v\u00e0 ch\u1ea5t \u0111\u1ec7m<\/strong> (h\u1ec7 borat) \u2013 \u1ee9ng d\u1ee5ng quen thu\u1ed9c nh\u1ea5t l\u00e0 trong thu\u1ed1c nh\u1ecf m\u1eaft v\u00e0 ch\u1ebf ph\u1ea9m d\u00f9ng ngo\u00e0i.<\/p>\n

Th\u00f4ng tin nhanh<\/h2>\n\n\n\n\n\n\n
T\u00ean kh\u00e1c<\/td>\nBoracic acid, orthoboric acid, boron trihydroxide, E284, Borofax<\/td>\n<\/tr>\n
S\u1ed1 CAS<\/td>\n10043-35-3 (acid orthoboric); 13460-50-9 (acid metaboric)<\/td>\n<\/tr>\n
C\u00f4ng th\u1ee9c \u2013 KLPT<\/td>\nH3<\/sub>BO3<\/sub> \u2013 61,83; HBO2<\/sub> \u2013 43,82<\/td>\n<\/tr>\n
Nh\u00f3m ch\u1ee9c n\u0103ng<\/td>\nCh\u1ea5t b\u1ea3o qu\u1ea3n kh\u00e1ng khu\u1ea9n (ch\u1ea5t \u0111\u1ec7m)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u1ee8ng d\u1ee5ng trong b\u00e0o ch\u1ebf<\/h2>\n
    \n
  • Ch\u1ea5t b\u1ea3o qu\u1ea3n trong thu\u1ed1c nh\u1ecf m\u1eaft, m\u1ef9 ph\u1ea9m, thu\u1ed1c m\u1ee1, kem d\u00f9ng ngo\u00e0i; ch\u1ea5t b\u1ea3o qu\u1ea3n th\u1ef1c ph\u1ea9m.<\/li>\n
  • Ch\u1ea5t \u0111\u1ec7m<\/strong>: acid boric v\u00e0 mu\u1ed1i borat c\u00f3 kh\u1ea3 n\u0103ng \u0111\u1ec7m t\u1ed1t, d\u00f9ng \u0111i\u1ec1u ch\u1ec9nh pH ch\u1ebf ph\u1ea9m d\u00f9ng ngo\u00e0i nh\u01b0 thu\u1ed1c nh\u1ecf m\u1eaft.<\/li>\n
  • Tr\u01b0\u1edbc \u0111\u00e2y d\u00f9ng l\u00e0m ch\u1ea5t s\u00e1t khu\u1ea9n nh\u1eb9 \u1edf n\u1ed3ng \u0111\u1ed9 lo\u00e3ng, nay \u0111\u00e3 \u0111\u01b0\u1ee3c thay b\u1eb1ng c\u00e1c ch\u1ea5t hi\u1ec7u qu\u1ea3 h\u01a1n, \u00edt \u0111\u1ed9c h\u01a1n.<\/li>\n<\/ul>\n

    M\u00f4 t\u1ea3 v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n
      \n
    • B\u1ed9t k\u1ebft tinh tr\u1eafng h\u00fat \u1ea9m, phi\u1ebfn b\u00f3ng kh\u00f4ng m\u00e0u ho\u1eb7c tinh th\u1ec3 tr\u1eafng.<\/li>\n
    • pH dung d\u1ecbch 5%: 3,5\u20134,1.<\/li>\n
    • N\u00f3ng ch\u1ea3y kho\u1ea3ng 171 \u00b0C. Khi \u0111un ch\u1eadm, m\u1ea5t n\u01b0\u1edbc d\u1ea7n t\u1ea1o acid metaboric (HBO2<\/sub>), acid tetraboric (H2<\/sub>B4<\/sub>O7<\/sub>), v\u00e0 \u1edf nhi\u1ec7t \u0111\u1ed9 cao h\u01a1n l\u00e0 bor trioxyd (B2<\/sub>O3<\/sub>).<\/li>\n
    • Tan trong n\u01b0\u1edbc, ethanol, glycerin; \u0111\u1ed9 tan trong n\u01b0\u1edbc t\u0103ng khi th\u00eam acid hydrocloric, citric ho\u1eb7c tartaric.<\/li>\n<\/ul>\n

      \u0110\u1ed9 \u1ed5n \u0111\u1ecbnh v\u00e0 b\u1ea3o qu\u1ea3n<\/h2>\n

      Acid boric h\u00fat \u1ea9m \u2013 b\u1ea3o qu\u1ea3n trong bao b\u00ec k\u00edn kh\u00ed. Bao b\u00ec ph\u1ea3i ghi nh\u00e3n “Kh\u00f4ng d\u00f9ng \u0111\u01b0\u1eddng u\u1ed1ng”<\/strong> (Not for Internal Use).<\/p>\n

      T\u01b0\u01a1ng k\u1ef5<\/h2>\n
        \n
      • T\u01b0\u01a1ng k\u1ef5 v\u1edbi base m\u1ea1nh v\u00e0 kim lo\u1ea1i ki\u1ec1m; ph\u1ea3n \u1ee9ng m\u00e3nh li\u1ec7t v\u1edbi kali v\u00e0 anhydrid acid.<\/li>\n
      • T\u1ea1o ph\u1ee9c v\u1edbi glycerin \u2013 ph\u1ee9c n\u00e0y l\u00e0 acid m\u1ea1nh h\u01a1n acid boric (c\u1ea7n l\u01b0u \u00fd khi t\u00ednh pH c\u00f4ng th\u1ee9c c\u00f3 glycerin).<\/li>\n<\/ul>\n

        S\u1ea3n xu\u1ea5t<\/h2>\n

        C\u00f3 trong t\u1ef1 nhi\u00ean d\u01b0\u1edbi d\u1ea1ng kho\u00e1ng sassolit, nh\u01b0ng ph\u1ea7n l\u1edbn \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t b\u1eb1ng c\u00e1ch cho borat v\u00f4 c\u01a1 (natri borat, calci borat \u2013 colemanit) ph\u1ea3n \u1ee9ng v\u1edbi acid sulfuric trong n\u01b0\u1edbc \u1edf kho\u1ea3ng 90 \u00b0C; l\u1ecdc b\u1ecf calci sulfat r\u1ed3i l\u00e0m l\u1ea1nh \u0111\u1ec3 k\u1ebft tinh acid boric.<\/p>\n

        An to\u00e0n v\u00e0 thao t\u00e1c<\/h2>\n

        Acid boric k\u00ecm khu\u1ea9n y\u1ebfu v\u00e0 \u0111\u1ed9c khi d\u00f9ng \u0111\u01b0\u1eddng trong<\/strong>, n\u00ean ch\u1ec9 d\u00f9ng ngo\u00e0i (tuy v\u1eady t\u1eebng c\u00f3 trong m\u1ed9t s\u1ed1 thu\u1ed1c ti\u00eam t\u0129nh m\u1ea1ch \u0111\u01b0\u1ee3c ph\u00ea duy\u1ec7t t\u1ea1i M\u1ef9 v\u00e0 Nh\u1eadt \u1edf h\u00e0m l\u01b0\u1ee3ng t\u00e1 d\u01b0\u1ee3c). Acid boric h\u1ea5p thu qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, qua da t\u1ed5n th\u01b0\u01a1ng, v\u1ebft th\u01b0\u01a1ng v\u00e0 ni\u00eam m\u1ea1c (\u00edt th\u1ea5m qua da l\u00e0nh) \u2013 v\u00ec v\u1eady kh\u00f4ng c\u00f2n khuy\u1ebfn c\u00e1o d\u00f9ng r\u1eeda khoang c\u01a1 th\u1ec3 hay b\u00f4i l\u00ean v\u1ebft th\u01b0\u01a1ng. Ng\u1ed9 \u0111\u1ed9c g\u00e2y \u0111au b\u1ee5ng, ti\u00eau ch\u1ea3y, n\u00f4n, ban \u0111\u1ecf da ni\u00eam m\u1ea1c, c\u00f3 th\u1ec3 co gi\u1eadt, s\u1ed1t cao, t\u1ed5n th\u01b0\u01a1ng \u1ed1ng th\u1eadn; \u0111\u00e3 c\u00f3 t\u1eed vong \u1edf tr\u1ebb nh\u1ecf v\u1edbi l\u01b0\u1ee3ng d\u01b0\u1edbi 5 g, ng\u01b0\u1eddi l\u1edbn 5\u201320 g, ph\u1ea7n l\u1edbn do u\u1ed1ng nh\u1ea7m dung d\u1ecbch ho\u1eb7c r\u1eafc b\u1ed9t l\u00ean da tr\u1ea7y x\u01b0\u1edbc.<\/p>\n

        Gi\u1edbi h\u1ea1n ph\u01a1i nhi\u1ec5m (PEL): 15 mg\/m\u00b3 b\u1ee5i to\u00e0n ph\u1ea7n, 5 mg\/m\u00b3 b\u1ee5i h\u00f4 h\u1ea5p. Khi thao t\u00e1c d\u00f9ng g\u0103ng tay, k\u00ednh, qu\u1ea7n \u00e1o b\u1ea3o h\u1ed9 v\u00e0 m\u1eb7t n\u1ea1.<\/p>\n

        T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n
          \n
        • C\u00f3 trong FDA Inactive Ingredients Guide (ti\u00eam t\u0129nh m\u1ea1ch, nh\u1ecf m\u1eaft, nh\u1ecf tai, d\u00f9ng ngo\u00e0i).<\/li>\n
        • \u0110\u01b0\u1ee3c ch\u1ea5p nh\u1eadn l\u00e0 ph\u1ee5 gia th\u1ef1c ph\u1ea9m t\u1ea1i ch\u00e2u \u00c2u; b\u1ecb h\u1ea1n ch\u1ebf trong m\u1ef9 ph\u1ea9m t\u1ea1i Anh; c\u00f3 trong danh m\u1ee5c t\u00e1 d\u01b0\u1ee3c \u0111\u01b0\u1ee3c ch\u1ea5p nh\u1eadn c\u1ee7a Canada.<\/li>\n
        • C\u00f3 chuy\u00ean lu\u1eadn trong JP, Ph.Eur. v\u00e0 USP-NF.<\/li>\n<\/ul>\n

          Ch\u1ea5t li\u00ean quan:<\/strong> natri borat.<\/p>\n

          Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n

          N\u1ed9i dung \u0111\u01b0\u1ee3c CPC1 bi\u00ean so\u1ea1n, t\u00f3m l\u01b0\u1ee3c c\u00f3 ch\u1ecdn l\u1ecdc t\u1eeb chuy\u00ean lu\u1eadn Boric Acid<\/em> trong:
          \nRowe R.C., Sheskey P.J., Owen S.C. (ch\u1ee7 bi\u00ean). Handbook of Pharmaceutical Excipients<\/em>, \u1ea5n b\u1ea3n 5.
          \nPharmaceutical Press (London) & American Pharmacists Association (Washington DC), 2006.
          \nB\u00e0i vi\u1ebft kh\u00f4ng sao ch\u00e9p nguy\u00ean v\u0103n t\u00e0i li\u1ec7u g\u1ed1c; c\u00e1c s\u1ed1 li\u1ec7u k\u1ef9 thu\u1eadt \u0111\u01b0\u1ee3c d\u1eabn l\u1ea1i t\u1eeb t\u00e0i li\u1ec7u n\u00e0y.<\/p>\n

          \u1ea2nh minh h\u1ecda: c\u00f4ng th\u1ee9c c\u1ea5u t\u1ea1o do CPC1 v\u1ebd l\u1ea1i t\u1eeb d\u1eef li\u1ec7u c\u1ea5u tr\u00fac h\u00f3a h\u1ecdc c\u00f4ng khai.<\/em><\/p>\n

          L\u01b0u \u00fd: th\u00f4ng tin mang t\u00ednh tham kh\u1ea3o cho ng\u01b0\u1eddi l\u00e0m chuy\u00ean m\u00f4n b\u00e0o ch\u1ebf, d\u1ef1a tr\u00ean \u1ea5n b\u1ea3n n\u0103m 2006.
          \nTi\u00eau chu\u1ea9n ch\u1ea5t l\u01b0\u1ee3ng v\u00e0 t\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd c\u00f3 th\u1ec3 \u0111\u00e3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu d\u01b0\u1ee3c \u0111i\u1ec3n v\u00e0 quy \u0111\u1ecbnh
          \nhi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

          Acid boric \u2013 ch\u1ea5t b\u1ea3o qu\u1ea3n, ch\u1ea5t \u0111\u1ec7m trong thu\u1ed1c nh\u1ecf m\u1eaft Acid boric (orthoboric acid, E284) l\u00e0 acid v\u00f4 c\u01a1 y\u1ebfu, c\u00f3 t\u00ednh k\u00ecm khu\u1ea9n nh\u1eb9. Trong b\u00e0o ch\u1ebf, acid boric \u0111\u01b0\u1ee3c d\u00f9ng l\u00e0m ch\u1ea5t b\u1ea3o qu\u1ea3n v\u00e0 ch\u1ea5t \u0111\u1ec7m (h\u1ec7 borat) \u2013 \u1ee9ng d\u1ee5ng quen thu\u1ed9c nh\u1ea5t l\u00e0 trong thu\u1ed1c nh\u1ecf m\u1eaft v\u00e0 […]<\/p>","protected":false},"author":1,"featured_media":2181,"comment_status":"","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[122],"tags":[],"class_list":["post-2182","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ta-duoc"],"blocksy_meta":[],"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/acid-boric.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/acid-boric-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/acid-boric-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/acid-boric-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/acid-boric-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/acid-boric.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/acid-boric.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/acid-boric-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Acid boric \u2013 ch\u1ea5t b\u1ea3o qu\u1ea3n, ch\u1ea5t \u0111\u1ec7m trong thu\u1ed1c nh\u1ecf m\u1eaft Acid boric (orthoboric acid, E284) l\u00e0 acid v\u00f4 c\u01a1 y\u1ebfu, c\u00f3 t\u00ednh k\u00ecm khu\u1ea9n nh\u1eb9. Trong b\u00e0o ch\u1ebf, acid boric \u0111\u01b0\u1ee3c d\u00f9ng l\u00e0m ch\u1ea5t b\u1ea3o qu\u1ea3n v\u00e0 ch\u1ea5t \u0111\u1ec7m (h\u1ec7 borat) \u2013 \u1ee9ng d\u1ee5ng quen thu\u1ed9c nh\u1ea5t l\u00e0 trong thu\u1ed1c nh\u1ecf m\u1eaft v\u00e0…","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2182","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=2182"}],"version-history":[{"count":0,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/2182\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2181"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=2182"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=2182"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=2182"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}