{"id":1034,"date":"2025-05-29T10:06:37","date_gmt":"2025-05-29T10:06:37","guid":{"rendered":"http:\/\/http:\/\/chempharco.com\/2025\/05\/29\/nguyen-lieu-resveratrol-98\/"},"modified":"2026-09-28T20:57:44","modified_gmt":"2026-09-28T13:57:44","slug":"nguyen-lieu-resveratrol-98","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/nguyen-lieu-resveratrol-98\/","title":{"rendered":"Resveratrol: c\u1ea5u t\u1ea1o, \u0111\u1ed3ng ph\u00e2n trans\/cis, ngu\u1ed3n g\u1ed1c v\u00e0 s\u1ea3n xu\u1ea5t"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Resveratrol: c\u1ea5u t\u1ea1o, \u0111\u1ed3ng ph\u00e2n trans\/cis, ngu\u1ed3n g\u1ed1c v\u00e0 s\u1ea3n xu\u1ea5t<\/h1>\n<p><strong>Resveratrol<\/strong> l\u00e0 m\u1ed9t <strong>stilbenoid<\/strong>, h\u1ee3p ch\u1ea5t phenol do th\u1ef1c v\u1eadt t\u1ea1o ra \u0111\u1ec3 t\u1ef1 v\u1ec7 khi b\u1ecb n\u1ea5m t\u1ea5n c\u00f4ng, b\u1ecb t\u1ed5n th\u01b0\u01a1ng ho\u1eb7c b\u1ecb chi\u1ebfu tia UV (phytoalexin). Ch\u1ea5t n\u1ed5i ti\u1ebfng v\u00ec c\u00f3 trong v\u1ecf nho v\u00e0 r\u01b0\u1ee3u vang \u0111\u1ecf, nh\u01b0ng ngu\u1ed3n th\u01b0\u01a1ng m\u1ea1i ch\u1ee7 y\u1ebfu l\u00e0 r\u1ec5 c\u00e2y <strong>c\u1ed1t kh\u00ed c\u1ee7<\/strong> (<em>Reynoutria japonica<\/em>, t\u00ean c\u0169 <em>Polygonum cuspidatum<\/em>).<\/p>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean g\u1ecdi<\/td>\n<td>Resveratrol, 3,5,4&#8242;-trihydroxy-trans-stilben<\/td>\n<\/tr>\n<tr>\n<td>C\u00f4ng th\u1ee9c, kh\u1ed1i l\u01b0\u1ee3ng mol<\/td>\n<td>C<sub>14<\/sub>H<sub>12<\/sub>O<sub>3<\/sub> \u2013 228,25 g\/mol<\/td>\n<\/tr>\n<tr>\n<td>S\u1ed1 CAS<\/td>\n<td>501-36-0 (trans-resveratrol)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>C\u1ea5u t\u1ea1o v\u00e0 t\u00ednh ch\u1ea5t<\/h2>\n<ul>\n<li>Hai v\u00f2ng phenol n\u1ed1i v\u1edbi nhau qua m\u1ed9t li\u00ean k\u1ebft \u0111\u00f4i C=C, n\u00ean c\u00f3 hai \u0111\u1ed3ng ph\u00e2n: <strong>trans<\/strong> (d\u1ea1ng ch\u00ednh, \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u nhi\u1ec1u nh\u1ea5t) v\u00e0 <strong>cis<\/strong>.<\/li>\n<li><strong>Nh\u1ea1y v\u1edbi \u00e1nh s\u00e1ng<\/strong>: tia UV chuy\u1ec3n trans-resveratrol th\u00e0nh cis-resveratrol. Nguy\u00ean li\u1ec7u v\u00e0 s\u1ea3n ph\u1ea9m c\u1ea7n bao b\u00ec c\u1ea3n quang.<\/li>\n<li>B\u1ed9t m\u00e0u tr\u1eafng \u0111\u1ebfn tr\u1eafng ng\u00e0 (d\u1ea1ng tinh khi\u1ebft cao) ho\u1eb7c n\u00e2u nh\u1ea1t (d\u1ea1ng chi\u1ebft \u0111\u1ed9 tinh khi\u1ebft th\u1ea5p). <strong>R\u1ea5t \u00edt tan trong n\u01b0\u1edbc<\/strong>, tan trong ethanol, DMSO.<\/li>\n<\/ul>\n<h2>Ngu\u1ed3n g\u1ed1c v\u00e0 s\u1ea3n xu\u1ea5t<\/h2>\n<ul>\n<li><strong>Chi\u1ebft t\u1eeb c\u1ed1t kh\u00ed c\u1ee7<\/strong>: r\u1ec5 ch\u1ee9a l\u01b0\u1ee3ng l\u1edbn polydatin (glycosid c\u1ee7a resveratrol); th\u1ee7y ph\u00e2n b\u1eb1ng enzym ho\u1eb7c acid \u0111\u1ec3 gi\u1ea3i ph\u00f3ng resveratrol, r\u1ed3i tinh ch\u1ebf. Nh\u00e3n th\u01b0\u1eddng ghi \u0111\u1ed9 tinh khi\u1ebft (v\u00ed d\u1ee5 50%, 98%).<\/li>\n<li><strong>T\u1ed5ng h\u1ee3p h\u00f3a h\u1ecdc<\/strong> v\u00e0 <strong>l\u00ean men<\/strong> (n\u1ea5m men \u0111\u01b0\u1ee3c c\u1ea3i bi\u1ebfn), cho trans-resveratrol \u0111\u1ed9 tinh khi\u1ebft cao.<\/li>\n<\/ul>\n<h2>Applications<\/h2>\n<ul>\n<li>Th\u1ef1c ph\u1ea9m b\u1ed5 sung.<\/li>\n<li>M\u1ef9 ph\u1ea9m: ch\u1ea5t ch\u1ed1ng oxy h\u00f3a trong serum, kem d\u01b0\u1ee1ng.<\/li>\n<\/ul>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd<\/h2>\n<p>T\u1ea1i Li\u00ean minh ch\u00e2u \u00c2u, trans-resveratrol \u0111\u01b0\u1ee3c c\u1ea5p ph\u00e9p l\u00e0 <strong>th\u1ef1c ph\u1ea9m m\u1edbi<\/strong> (novel food) d\u00f9ng trong th\u1ef1c ph\u1ea9m b\u1ed5 sung, k\u00e8m gi\u1edbi h\u1ea1n l\u01b0\u1ee3ng d\u00f9ng h\u1eb1ng ng\u00e0y.<\/p>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd t\u1ea1i Vi\u1ec7t Nam<\/h2>\n<p>Khi d\u00f9ng l\u00e0m th\u00e0nh ph\u1ea7n c\u1ee7a th\u1ef1c ph\u1ea9m ho\u1eb7c th\u1ef1c ph\u1ea9m b\u1ea3o v\u1ec7 s\u1ee9c kh\u1ecfe, s\u1ea3n ph\u1ea9m tu\u00e2n theo Lu\u1eadt An to\u00e0n th\u1ef1c ph\u1ea9m, Ngh\u1ecb \u0111\u1ecbnh 15\/2018\/N\u0110-CP v\u00e0 c\u00e1c v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh c\u1ee7a B\u1ed9 Y t\u1ebf. Doanh nghi\u1ec7p c\u1ea7n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n m\u1edbi nh\u1ea5t tr\u01b0\u1edbc khi x\u00e2y d\u1ef1ng c\u00f4ng th\u1ee9c.<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<ul>\n<li>Wikipedia \u2013 Resveratrol \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Resveratrol\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Resveratrol<\/a><\/li>\n<li>Wikidata \u2013 \u0111\u1ecbnh danh h\u00f3a h\u1ecdc (CAS, c\u00f4ng th\u1ee9c) \u2014 <a href=\"https:\/\/www.wikidata.org\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.wikidata.org\/<\/a><\/li>\n<\/ul>\n<p><em>B\u00e0i vi\u1ebft cung c\u1ea5p th\u00f4ng tin ki\u1ebfn th\u1ee9c chung v\u1ec1 ch\u1ea5t\/nguy\u00ean li\u1ec7u, t\u1ed5ng h\u1ee3p v\u00e0 di\u1ec5n gi\u1ea3i t\u1eeb c\u00e1c ngu\u1ed3n c\u00f4ng khai n\u00eau tr\u00ean. N\u1ed9i dung n\u00e0y kh\u00f4ng thay th\u1ebf \u00fd ki\u1ebfn c\u1ee7a c\u01a1 quan qu\u1ea3n l\u00fd hay chuy\u00ean gia y t\u1ebf. C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft. Quy \u0111\u1ecbnh ph\u00e1p l\u00fd c\u00f3 th\u1ec3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Resveratrol: c\u1ea5u t\u1ea1o, \u0111\u1ed3ng ph\u00e2n trans\/cis, ngu\u1ed3n g\u1ed1c v\u00e0 s\u1ea3n xu\u1ea5t Resveratrol l\u00e0 m\u1ed9t stilbenoid, h\u1ee3p ch\u1ea5t phenol do th\u1ef1c v\u1eadt t\u1ea1o ra \u0111\u1ec3 t\u1ef1 v\u1ec7 khi b\u1ecb n\u1ea5m t\u1ea5n c\u00f4ng, b\u1ecb t\u1ed5n th\u01b0\u01a1ng ho\u1eb7c b\u1ecb chi\u1ebfu tia UV (phytoalexin). Ch\u1ea5t n\u1ed5i ti\u1ebfng v\u00ec c\u00f3 trong v\u1ecf nho v\u00e0 r\u01b0\u1ee3u vang \u0111\u1ecf, nh\u01b0ng ngu\u1ed3n th\u01b0\u01a1ng [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2950,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[121],"tags":[],"class_list":["post-1034","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-kien-thuc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/resveratrol.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/resveratrol-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/resveratrol-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/resveratrol-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/resveratrol-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/resveratrol.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/resveratrol.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/resveratrol-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Resveratrol: c\u1ea5u t\u1ea1o, \u0111\u1ed3ng ph\u00e2n trans\/cis, ngu\u1ed3n g\u1ed1c v\u00e0 s\u1ea3n xu\u1ea5t Resveratrol l\u00e0 m\u1ed9t stilbenoid, h\u1ee3p ch\u1ea5t phenol do th\u1ef1c v\u1eadt t\u1ea1o ra \u0111\u1ec3 t\u1ef1 v\u1ec7 khi b\u1ecb n\u1ea5m t\u1ea5n c\u00f4ng, b\u1ecb t\u1ed5n th\u01b0\u01a1ng ho\u1eb7c b\u1ecb chi\u1ebfu tia UV (phytoalexin). Ch\u1ea5t n\u1ed5i ti\u1ebfng v\u00ec c\u00f3 trong v\u1ecf nho v\u00e0 r\u01b0\u1ee3u vang \u0111\u1ecf, nh\u01b0ng ngu\u1ed3n th\u01b0\u01a1ng&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/1034","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=1034"}],"version-history":[{"count":2,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/1034\/revisions"}],"predecessor-version":[{"id":3083,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/1034\/revisions\/3083"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2950"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=1034"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=1034"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=1034"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}