{"id":1022,"date":"2025-05-29T10:01:39","date_gmt":"2025-05-29T10:01:39","guid":{"rendered":"http:\/\/http:\/\/chempharco.com\/2025\/05\/29\/nguyen-lieu-methyl-salicylate\/"},"modified":"2026-09-28T20:56:00","modified_gmt":"2026-09-28T13:56:00","slug":"nguyen-lieu-methyl-salicylate","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/nguyen-lieu-methyl-salicylate\/","title":{"rendered":"Methyl salicylate (d\u1ea7u gi\u00f3 \u0111\u00f4ng xanh): c\u1ea5u t\u1ea1o, t\u00ednh ch\u1ea5t v\u00e0 gi\u1edbi h\u1ea1n"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Methyl salicylate (d\u1ea7u gi\u00f3 \u0111\u00f4ng xanh): c\u1ea5u t\u1ea1o, t\u00ednh ch\u1ea5t v\u00e0 gi\u1edbi h\u1ea1n<\/h1>\n<p><strong>Methyl salicylate<\/strong> l\u00e0 ester methyl c\u1ee7a acid salicylic, ch\u1ea5t l\u1ecfng c\u00f3 <strong>m\u00f9i th\u01a1m \u0111\u1eb7c tr\u01b0ng &#8220;d\u1ea7u gi\u00f3&#8221;<\/strong>, &#8220;cao d\u00e1n&#8221;. \u0110\u00e2y l\u00e0 th\u00e0nh ph\u1ea7n ch\u00ednh c\u1ee7a <strong>d\u1ea7u gi\u00f3 \u0111\u00f4ng xanh<\/strong> (wintergreen oil, t\u1eeb c\u00e2y <em>Gaultheria procumbens<\/em>) v\u00e0 tinh d\u1ea7u v\u1ecf c\u00e2y b\u1ea1ch d\u01b0\u01a1ng ng\u1ecdt (<em>Betula lenta<\/em>).<\/p>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean g\u1ecdi<\/td>\n<td>Methyl salicylate, methyl 2-hydroxybenzoat, d\u1ea7u gi\u00f3 \u0111\u00f4ng xanh<\/td>\n<\/tr>\n<tr>\n<td>C\u00f4ng th\u1ee9c, kh\u1ed1i l\u01b0\u1ee3ng mol<\/td>\n<td>C<sub>8<\/sub>H<sub>8<\/sub>O<sub>3<\/sub> \u2013 152,15 g\/mol<\/td>\n<\/tr>\n<tr>\n<td>S\u1ed1 CAS<\/td>\n<td>119-36-8<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>T\u00ednh ch\u1ea5t<\/h2>\n<ul>\n<li>Ch\u1ea5t l\u1ecfng kh\u00f4ng m\u00e0u \u0111\u1ebfn v\u00e0ng nh\u1ea1t, m\u00f9i th\u01a1m m\u1ea1nh, h\u01a1i ng\u1ecdt. \u00cdt tan trong n\u01b0\u1edbc, tan trong ethanol, d\u1ea7u.<\/li>\n<li>H\u1ea5p thu t\u1ed1t qua da. Khi v\u00e0o c\u01a1 th\u1ec3, methyl salicylate b\u1ecb th\u1ee7y ph\u00e2n th\u00e0nh acid salicylic.<\/li>\n<\/ul>\n<h2>S\u1ea3n xu\u1ea5t<\/h2>\n<p>Methyl salicylate th\u01b0\u01a1ng m\u1ea1i ch\u1ee7 y\u1ebfu \u0111\u01b0\u1ee3c <strong>t\u1ed5ng h\u1ee3p<\/strong> b\u1eb1ng ph\u1ea3n \u1ee9ng ester h\u00f3a acid salicylic v\u1edbi methanol, x\u00fac t\u00e1c acid. D\u1ea7u gi\u00f3 \u0111\u00f4ng xanh t\u1ef1 nhi\u00ean \u0111\u01b0\u1ee3c ch\u01b0ng c\u1ea5t l\u00f4i cu\u1ed1n h\u01a1i n\u01b0\u1edbc t\u1eeb l\u00e1, sau khi \u0111\u1ec3 enzym trong l\u00e1 gi\u1ea3i ph\u00f3ng methyl salicylate t\u1eeb glycosid.<\/p>\n<h2>Applications<\/h2>\n<ul>\n<li>Ch\u1ea5t t\u1ea1o h\u01b0\u01a1ng trong kem \u0111\u00e1nh r\u0103ng, n\u01b0\u1edbc s\u00fac mi\u1ec7ng, k\u1eb9o cao su, m\u1ed9t s\u1ed1 \u0111\u1ed3 u\u1ed1ng (li\u1ec1u r\u1ea5t th\u1ea5p).<\/li>\n<li>M\u1ef9 ph\u1ea9m, s\u1ea3n ph\u1ea9m ch\u0103m s\u00f3c c\u00e1 nh\u00e2n (theo gi\u1edbi h\u1ea1n).<\/li>\n<li>D\u1ea7u xoa, cao d\u00e1n d\u00f9ng ngo\u00e0i thu\u1ed9c nh\u00f3m thu\u1ed1c; c\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft.<\/li>\n<\/ul>\n<h2>An to\u00e0n<\/h2>\n<ul>\n<li><strong>Nu\u1ed1t ph\u1ea3i l\u01b0\u1ee3ng nh\u1ecf d\u1ea1ng \u0111\u1eadm \u0111\u1eb7c c\u00f3 th\u1ec3 g\u00e2y ng\u1ed9 \u0111\u1ed9c salicylat nghi\u00eam tr\u1ecdng<\/strong>, \u0111\u1eb7c bi\u1ec7t v\u1edbi tr\u1ebb em. S\u1ea3n ph\u1ea9m ch\u1ee9a methyl salicylate c\u1ea7n bao b\u00ec an to\u00e0n v\u00e0 \u0111\u1ec3 xa t\u1ea7m tay tr\u1ebb em.<\/li>\n<li><strong>EU<\/strong>: t\u1eeb 17\/12\/2022, methyl salicylate thu\u1ed9c Ph\u1ee5 l\u1ee5c III (Quy \u0111\u1ecbnh (EU) 2022\/1531), v\u1edbi gi\u1edbi h\u1ea1n theo lo\u1ea1i s\u1ea3n ph\u1ea9m, v\u00ed d\u1ee5 0,06% trong ph\u1ea7n l\u1edbn s\u1ea3n ph\u1ea9m l\u01b0u tr\u00ean da v\u00e0 s\u1ea3n ph\u1ea9m x\u1ea3, 0,6% trong n\u01b0\u1edbc s\u00fac mi\u1ec7ng, 2,52% trong kem \u0111\u00e1nh r\u0103ng. Kh\u00f4ng d\u00f9ng trong s\u1ea3n ph\u1ea9m cho tr\u1ebb d\u01b0\u1edbi 6 tu\u1ed5i, tr\u1eeb kem \u0111\u00e1nh r\u0103ng.<\/li>\n<\/ul>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd t\u1ea1i Vi\u1ec7t Nam<\/h2>\n<p>M\u1ef9 ph\u1ea9m t\u1ea1i Vi\u1ec7t Nam \u0111\u01b0\u1ee3c qu\u1ea3n l\u00fd theo Th\u00f4ng t\u01b0 06\/2011\/TT-BYT v\u00e0 Hi\u1ec7p \u0111\u1ecbnh h\u00f2a h\u1ee3p trong qu\u1ea3n l\u00fd m\u1ef9 ph\u1ea9m ASEAN. Danh m\u1ee5c ch\u1ea5t c\u1ea5m, ch\u1ea5t h\u1ea1n ch\u1ebf v\u00e0 ch\u1ea5t b\u1ea3o qu\u1ea3n c\u1ee7a ASEAN ph\u1ea7n l\u1edbn t\u01b0\u01a1ng \u0111\u1ed3ng v\u1edbi EU v\u00e0 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadt \u0111\u1ecbnh k\u1ef3. Doanh nghi\u1ec7p c\u1ea7n \u0111\u1ed1i chi\u1ebfu ph\u1ee5 l\u1ee5c ASEAN hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi x\u00e2y d\u1ef1ng c\u00f4ng th\u1ee9c.<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<ul>\n<li>Wikipedia \u2013 Methyl salicylate \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Methyl_salicylate\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Methyl_salicylate<\/a><\/li>\n<li>Wikidata \u2013 \u0111\u1ecbnh danh h\u00f3a h\u1ecdc (CAS, c\u00f4ng th\u1ee9c) \u2014 <a href=\"https:\/\/www.wikidata.org\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.wikidata.org\/<\/a><\/li>\n<li>BAV-Institut \u2013 Methyl salicylate in cosmetic products: maximum quantity restriction since December 2022 \u2014 <a href=\"https:\/\/www.bav-institut.de\/en\/news\/methyl-salicylate-in-cosmetic-products-maximum-quantity-restriction-since-december-2022\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.bav-institut.de\/en\/news\/methyl-salicylate-in-cosmetic-products-maximum-quantity-restriction-since-december-2022<\/a><\/li>\n<\/ul>\n<p><em>B\u00e0i vi\u1ebft cung c\u1ea5p th\u00f4ng tin ki\u1ebfn th\u1ee9c chung v\u1ec1 ch\u1ea5t\/nguy\u00ean li\u1ec7u, t\u1ed5ng h\u1ee3p v\u00e0 di\u1ec5n gi\u1ea3i t\u1eeb c\u00e1c ngu\u1ed3n c\u00f4ng khai n\u00eau tr\u00ean. N\u1ed9i dung n\u00e0y kh\u00f4ng thay th\u1ebf \u00fd ki\u1ebfn c\u1ee7a c\u01a1 quan qu\u1ea3n l\u00fd hay chuy\u00ean gia y t\u1ebf. C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft. Quy \u0111\u1ecbnh ph\u00e1p l\u00fd c\u00f3 th\u1ec3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Methyl salicylate (d\u1ea7u gi\u00f3 \u0111\u00f4ng xanh): c\u1ea5u t\u1ea1o, t\u00ednh ch\u1ea5t v\u00e0 gi\u1edbi h\u1ea1n Methyl salicylate l\u00e0 ester methyl c\u1ee7a acid salicylic, ch\u1ea5t l\u1ecfng c\u00f3 m\u00f9i th\u01a1m \u0111\u1eb7c tr\u01b0ng &#8220;d\u1ea7u gi\u00f3&#8221;, &#8220;cao d\u00e1n&#8221;. \u0110\u00e2y l\u00e0 th\u00e0nh ph\u1ea7n ch\u00ednh c\u1ee7a d\u1ea7u gi\u00f3 \u0111\u00f4ng xanh (wintergreen oil, t\u1eeb c\u00e2y Gaultheria procumbens) v\u00e0 tinh d\u1ea7u v\u1ecf c\u00e2y b\u1ea1ch d\u01b0\u01a1ng [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2939,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[121],"tags":[],"class_list":["post-1022","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-kien-thuc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/methyl-salicylate.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/methyl-salicylate-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/methyl-salicylate-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/methyl-salicylate-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/methyl-salicylate-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/methyl-salicylate.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/methyl-salicylate.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/methyl-salicylate-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Methyl salicylate (d\u1ea7u gi\u00f3 \u0111\u00f4ng xanh): c\u1ea5u t\u1ea1o, t\u00ednh ch\u1ea5t v\u00e0 gi\u1edbi h\u1ea1n Methyl salicylate l\u00e0 ester methyl c\u1ee7a acid salicylic, ch\u1ea5t l\u1ecfng c\u00f3 m\u00f9i th\u01a1m \u0111\u1eb7c tr\u01b0ng &#8220;d\u1ea7u gi\u00f3&#8221;, &#8220;cao d\u00e1n&#8221;. \u0110\u00e2y l\u00e0 th\u00e0nh ph\u1ea7n ch\u00ednh c\u1ee7a d\u1ea7u gi\u00f3 \u0111\u00f4ng xanh (wintergreen oil, t\u1eeb c\u00e2y Gaultheria procumbens) v\u00e0 tinh d\u1ea7u v\u1ecf c\u00e2y b\u1ea1ch d\u01b0\u01a1ng&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/1022","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=1022"}],"version-history":[{"count":2,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/1022\/revisions"}],"predecessor-version":[{"id":3072,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/1022\/revisions\/3072"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2939"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=1022"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=1022"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=1022"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}