{"id":1007,"date":"2025-05-29T09:54:26","date_gmt":"2025-05-29T09:54:26","guid":{"rendered":"http:\/\/http:\/\/chempharco.com\/2025\/05\/29\/nguyen-lieu-hoa-chat-glypure-glycolic-acid\/"},"modified":"2026-09-28T20:52:36","modified_gmt":"2026-09-28T13:52:36","slug":"nguyen-lieu-hoa-chat-glypure-glycolic-acid","status":"publish","type":"post","link":"https:\/\/cpc1.vn\/en\/nguyen-lieu-hoa-chat-glypure-glycolic-acid\/","title":{"rendered":"Glycolic acid (AHA): c\u1ea5u t\u1ea1o, s\u1ea3n xu\u1ea5t, vai tr\u00f2 c\u1ee7a pH trong c\u00f4ng th\u1ee9c"},"content":{"rendered":"<h1 class=\"kt-tieu-de\">Glycolic acid (AHA): c\u1ea5u t\u1ea1o, s\u1ea3n xu\u1ea5t, vai tr\u00f2 c\u1ee7a pH trong c\u00f4ng th\u1ee9c<\/h1>\n<p><strong>Glycolic acid<\/strong> (acid glycolic) l\u00e0 <strong>alpha-hydroxy acid (AHA)<\/strong> nh\u1ecf nh\u1ea5t: ch\u1ec9 g\u1ed3m hai carbon, m\u1ed9t nh\u00f3m carboxyl v\u00e0 m\u1ed9t nh\u00f3m hydroxyl. Nh\u1edd ph\u00e2n t\u1eed nh\u1ecf, glycolic acid th\u1ea5m v\u00e0o l\u1edbp s\u1eebng t\u1ed1t v\u00e0 l\u00e0 AHA \u0111\u01b0\u1ee3c d\u00f9ng nhi\u1ec1u nh\u1ea5t trong m\u1ef9 ph\u1ea9m t\u1ea9y t\u1ebf b\u00e0o ch\u1ebft.<\/p>\n<h2>Th\u00f4ng tin nhanh<\/h2>\n<table>\n<tbody>\n<tr>\n<td>T\u00ean g\u1ecdi<\/td>\n<td>Glycolic acid, acid hydroxyacetic, acid 2-hydroxyethanoic<\/td>\n<\/tr>\n<tr>\n<td>C\u00f4ng th\u1ee9c, kh\u1ed1i l\u01b0\u1ee3ng mol<\/td>\n<td>C<sub>2<\/sub>H<sub>4<\/sub>O<sub>3<\/sub> \u2013 76,05 g\/mol<\/td>\n<\/tr>\n<tr>\n<td>S\u1ed1 CAS<\/td>\n<td>79-14-1<\/td>\n<\/tr>\n<tr>\n<td>T\u00ean INCI<\/td>\n<td>Glycolic Acid<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>T\u00ednh ch\u1ea5t v\u00e0 ngu\u1ed3n g\u1ed1c<\/h2>\n<ul>\n<li>D\u1ea1ng tinh khi\u1ebft l\u00e0 tinh th\u1ec3 kh\u00f4ng m\u00e0u, r\u1ea5t h\u00fat \u1ea9m; th\u01b0\u01a1ng m\u1ea1i ph\u1ed5 bi\u1ebfn \u1edf d\u1ea1ng <strong>dung d\u1ecbch 70%<\/strong> trong n\u01b0\u1edbc. Tan ho\u00e0n to\u00e0n trong n\u01b0\u1edbc.<\/li>\n<li>C\u00f3 t\u1ef1 nhi\u00ean trong m\u00eda, c\u1ee7 c\u1ea3i \u0111\u01b0\u1eddng, nho ch\u01b0a ch\u00edn. Glycolic acid c\u00f4ng nghi\u1ec7p ch\u1ee7 y\u1ebfu \u0111\u01b0\u1ee3c <strong>t\u1ed5ng h\u1ee3p<\/strong> (ph\u1ea3n \u1ee9ng carbonyl h\u00f3a formaldehyd, ho\u1eb7c th\u1ee7y ph\u00e2n acid cloroacetic), cho \u0111\u1ed9 tinh khi\u1ebft cao h\u01a1n d\u1ea1ng chi\u1ebft.<\/li>\n<\/ul>\n<h2>V\u00ec sao pH quan tr\u1ecdng<\/h2>\n<p>T\u00e1c \u0111\u1ed9ng c\u1ee7a AHA l\u00ean da ph\u1ee5 thu\u1ed9c l\u01b0\u1ee3ng acid \u1edf <strong>d\u1ea1ng t\u1ef1 do<\/strong> (ch\u01b0a b\u1ecb trung h\u00f2a), t\u1ee9c ph\u1ee5 thu\u1ed9c c\u1ea3 <strong>n\u1ed3ng \u0111\u1ed9<\/strong> l\u1eabn <strong>pH<\/strong>. Glycolic acid c\u00f3 pKa kho\u1ea3ng 3,8. \u1ede pH th\u1ea5p h\u01a1n, ph\u1ea7n acid t\u1ef1 do nhi\u1ec1u h\u01a1n n\u00ean t\u00e1c \u0111\u1ed9ng m\u1ea1nh h\u01a1n nh\u01b0ng d\u1ec5 k\u00edch \u1ee9ng h\u01a1n. C\u00f4ng th\u1ee9c th\u01b0\u1eddng \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ec9nh pH b\u1eb1ng ki\u1ec1m (natri hydroxid, amoniac, arginin) \u0111\u1ec3 c\u00e2n b\u1eb1ng gi\u1eefa hi\u1ec7u qu\u1ea3 v\u00e0 m\u1ee9c k\u00edch \u1ee9ng.<\/p>\n<h2>Applications<\/h2>\n<ul>\n<li>M\u1ef9 ph\u1ea9m: toner, serum, kem t\u1ea9y t\u1ebf b\u00e0o ch\u1ebft; s\u1ea3n ph\u1ea9m ch\u0103m s\u00f3c chuy\u00ean nghi\u1ec7p n\u1ed3ng \u0111\u1ed9 cao (ch\u1ec9 d\u00f9ng b\u1edfi ng\u01b0\u1eddi \u0111\u01b0\u1ee3c \u0111\u00e0o t\u1ea1o).<\/li>\n<li>C\u00f4ng nghi\u1ec7p: ch\u1ea5t t\u1ea9y r\u1eeda, x\u1eed l\u00fd b\u1ec1 m\u1eb7t kim lo\u1ea1i, thu\u1ed9c da; nguy\u00ean li\u1ec7u s\u1ea3n xu\u1ea5t polyme ph\u00e2n h\u1ee7y sinh h\u1ecdc (acid polyglycolic).<\/li>\n<\/ul>\n<h2>An to\u00e0n<\/h2>\n<ul>\n<li>AHA l\u00e0m da <strong>t\u0103ng nh\u1ea1y c\u1ea3m v\u1edbi \u00e1nh n\u1eafng<\/strong>. FDA Hoa K\u1ef3 khuy\u1ebfn ngh\u1ecb s\u1ea3n ph\u1ea9m ch\u1ee9a AHA c\u00f3 c\u1ea3nh b\u00e1o d\u00f9ng kem ch\u1ed1ng n\u1eafng trong th\u1eddi gian s\u1eed d\u1ee5ng v\u00e0 th\u00eam m\u1ed9t tu\u1ea7n sau khi ng\u1eebng.<\/li>\n<li>Dung d\u1ecbch \u0111\u1eadm \u0111\u1eb7c g\u00e2y \u0103n m\u00f2n da v\u00e0 m\u1eaft; c\u1ea7n b\u1ea3o h\u1ed9 khi thao t\u00e1c nguy\u00ean li\u1ec7u.<\/li>\n<\/ul>\n<h2>T\u00ecnh tr\u1ea1ng ph\u00e1p l\u00fd t\u1ea1i Vi\u1ec7t Nam<\/h2>\n<p>M\u1ef9 ph\u1ea9m t\u1ea1i Vi\u1ec7t Nam \u0111\u01b0\u1ee3c qu\u1ea3n l\u00fd theo Th\u00f4ng t\u01b0 06\/2011\/TT-BYT v\u00e0 Hi\u1ec7p \u0111\u1ecbnh h\u00f2a h\u1ee3p trong qu\u1ea3n l\u00fd m\u1ef9 ph\u1ea9m ASEAN. Danh m\u1ee5c ch\u1ea5t c\u1ea5m, ch\u1ea5t h\u1ea1n ch\u1ebf v\u00e0 ch\u1ea5t b\u1ea3o qu\u1ea3n c\u1ee7a ASEAN ph\u1ea7n l\u1edbn t\u01b0\u01a1ng \u0111\u1ed3ng v\u1edbi EU v\u00e0 \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadt \u0111\u1ecbnh k\u1ef3. Doanh nghi\u1ec7p c\u1ea7n \u0111\u1ed1i chi\u1ebfu ph\u1ee5 l\u1ee5c ASEAN hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi x\u00e2y d\u1ef1ng c\u00f4ng th\u1ee9c.<\/p>\n<h2>Ngu\u1ed3n tham kh\u1ea3o<\/h2>\n<ul>\n<li>Wikipedia \u2013 Glycolic acid \u2014 <a href=\"https:\/\/en.wikipedia.org\/wiki\/Glycolic_acid\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/en.wikipedia.org\/wiki\/Glycolic_acid<\/a><\/li>\n<li>Wikidata \u2013 \u0111\u1ecbnh danh h\u00f3a h\u1ecdc (CAS, c\u00f4ng th\u1ee9c) \u2014 <a href=\"https:\/\/www.wikidata.org\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.wikidata.org\/<\/a><\/li>\n<li>U.S. FDA \u2013 Alpha Hydroxy Acids (th\u00f4ng tin cho ng\u01b0\u1eddi ti\u00eau d\u00f9ng v\u1ec1 m\u1ef9 ph\u1ea9m) \u2014 <a href=\"https:\/\/www.fda.gov\/cosmetics\/cosmetic-ingredients\/alpha-hydroxy-acids\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.fda.gov\/cosmetics\/cosmetic-ingredients\/alpha-hydroxy-acids<\/a><\/li>\n<\/ul>\n<p><em>B\u00e0i vi\u1ebft cung c\u1ea5p th\u00f4ng tin ki\u1ebfn th\u1ee9c chung v\u1ec1 ch\u1ea5t\/nguy\u00ean li\u1ec7u, t\u1ed5ng h\u1ee3p v\u00e0 di\u1ec5n gi\u1ea3i t\u1eeb c\u00e1c ngu\u1ed3n c\u00f4ng khai n\u00eau tr\u00ean. N\u1ed9i dung n\u00e0y kh\u00f4ng thay th\u1ebf \u00fd ki\u1ebfn c\u1ee7a c\u01a1 quan qu\u1ea3n l\u00fd hay chuy\u00ean gia y t\u1ebf. C\u00f4ng d\u1ee5ng l\u00e0m thu\u1ed1c n\u1eb1m ngo\u00e0i ph\u1ea1m vi b\u00e0i vi\u1ebft. Quy \u0111\u1ecbnh ph\u00e1p l\u00fd c\u00f3 th\u1ec3 thay \u0111\u1ed5i \u2014 lu\u00f4n \u0111\u1ed1i chi\u1ebfu v\u0103n b\u1ea3n hi\u1ec7n h\u00e0nh tr\u01b0\u1edbc khi s\u1eed d\u1ee5ng.<\/em><\/p>","protected":false},"excerpt":{"rendered":"<p>Glycolic acid (AHA): c\u1ea5u t\u1ea1o, s\u1ea3n xu\u1ea5t, vai tr\u00f2 c\u1ee7a pH trong c\u00f4ng th\u1ee9c Glycolic acid (acid glycolic) l\u00e0 alpha-hydroxy acid (AHA) nh\u1ecf nh\u1ea5t: ch\u1ec9 g\u1ed3m hai carbon, m\u1ed9t nh\u00f3m carboxyl v\u00e0 m\u1ed9t nh\u00f3m hydroxyl. Nh\u1edd ph\u00e2n t\u1eed nh\u1ecf, glycolic acid th\u1ea5m v\u00e0o l\u1edbp s\u1eebng t\u1ed1t v\u00e0 l\u00e0 AHA \u0111\u01b0\u1ee3c d\u00f9ng nhi\u1ec1u nh\u1ea5t trong m\u1ef9 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2917,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[121],"tags":[],"class_list":["post-1007","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-kien-thuc"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":8}},"acf":[],"uagb_featured_image_src":{"full":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glycolic-acid.png",1200,675,false],"thumbnail":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glycolic-acid-150x150.png",150,150,true],"medium":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glycolic-acid-300x169.png",300,169,true],"medium_large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glycolic-acid-768x432.png",768,432,true],"large":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glycolic-acid-1024x576.png",1024,576,true],"1536x1536":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glycolic-acid.png",1200,675,false],"2048x2048":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glycolic-acid.png",1200,675,false],"trp-custom-language-flag":["https:\/\/cpc1.vn\/wp-content\/uploads\/2026\/09\/glycolic-acid-18x10.png",18,10,true]},"uagb_author_info":{"display_name":"cpc1vn","author_link":"https:\/\/cpc1.vn\/en\/author\/cpc1vn\/"},"uagb_comment_info":0,"uagb_excerpt":"Glycolic acid (AHA): c\u1ea5u t\u1ea1o, s\u1ea3n xu\u1ea5t, vai tr\u00f2 c\u1ee7a pH trong c\u00f4ng th\u1ee9c Glycolic acid (acid glycolic) l\u00e0 alpha-hydroxy acid (AHA) nh\u1ecf nh\u1ea5t: ch\u1ec9 g\u1ed3m hai carbon, m\u1ed9t nh\u00f3m carboxyl v\u00e0 m\u1ed9t nh\u00f3m hydroxyl. Nh\u1edd ph\u00e2n t\u1eed nh\u1ecf, glycolic acid th\u1ea5m v\u00e0o l\u1edbp s\u1eebng t\u1ed1t v\u00e0 l\u00e0 AHA \u0111\u01b0\u1ee3c d\u00f9ng nhi\u1ec1u nh\u1ea5t trong m\u1ef9&hellip;","_links":{"self":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/1007","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/comments?post=1007"}],"version-history":[{"count":2,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/1007\/revisions"}],"predecessor-version":[{"id":3050,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/posts\/1007\/revisions\/3050"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media\/2917"}],"wp:attachment":[{"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/media?parent=1007"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/categories?post=1007"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cpc1.vn\/en\/wp-json\/wp\/v2\/tags?post=1007"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}